Herrmann F, Müller P, Sorger D, Wolf T
Z Gesamte Inn Med. 1986 Apr 15;41(8):226-9.
The influence on the parameters of the thyroid gland BEI, T3-, T4- and TSH-serum level by the iodine-containing oral bile X-ray contrast remedy Falignost is demonstrated. Following a peripheral conversions inhibition from T4 to T3 by the contrast remedy the thyroid hormones in the serum are changed in different kind and duration. This influence is more expressed in patients with liver cirrhosis and continues. The risk of an iodine-induced hyperthyroidism is discussed. In the judgment of a possible disturbance of the function of the thyroid gland anamnestically is always to be asked the question about previous applications of iodine-containing drugs and it must be accordingly be taken into consideration.
研究显示了含碘口服胆道X线造影剂Falignost对甲状腺BEI参数以及血清T3、T4和TSH水平的影响。造影剂抑制了T4向T3的外周转化,血清中的甲状腺激素在种类和持续时间上发生了不同变化。这种影响在肝硬化患者中表现得更为明显且持续存在。文中讨论了碘诱发甲状腺功能亢进的风险。在判断甲状腺功能可能受到的干扰时,问诊既往使用含碘药物的情况始终是必要的,必须予以相应考虑。