Schoenmakers H J N, VAN Bohemen Ch G, Dieleman S J
Laboratory of Chemical Animal Physiology, and Section Comparative Endocrinology of the Zoological Laboratory, State University of Utrecht, 8 Padualaan, 3508 TB Utrecht.
Clinic for Obstetrics, A.I. and Reproduction, Veterinary Faculty, State University of Utrecht, 7 Yalelaan, 3508 TD Utrecht, The Netherlands.
Dev Growth Differ. 1981;23(2):125-135. doi: 10.1111/j.1440-169X.1981.00125.x.
Oocyte diameters and their frequency distribution, and various other data determined for the oestradiol-17 β treated female specimens of Asterias rubens proved to be significantly different from those for the control animals. The maturation index of the treated animals is 2.4, that of the control animals 1.4. Since the treated animals show a greater heterogeneity in development than the control animals, and because the diameter of the smallest oocytes is the same for both treated and control animals, a threshold size of the oocytes may be required before oocyte growth can be stimulated by oestradiol-17β, and before substances originating in the pyloric caeca are incorporated into the oocytes. Oestradiol-17β treatment caused a tenfold increase of the oestrone level in the ovaries, whereas a non-significant increase was observed in the pyloric caeca. This may indicate that in vivo oestradiol-17β is converted into oestrone in the ovaries but not in the pyloric caeca.
对经17β -雌二醇处理的红海星雌性标本测定的卵母细胞直径及其频率分布，以及其他各种数据，被证明与对照动物的这些数据有显著差异。处理组动物的成熟指数为2.4，对照组动物为1.4。由于处理组动物在发育过程中表现出比对照组动物更大的异质性，并且由于处理组和对照组动物中最小卵母细胞的直径相同，因此在卵母细胞生长能够被17β -雌二醇刺激之前，以及在源自幽门盲囊的物质被纳入卵母细胞之前，可能需要一个卵母细胞的阈值大小。17β -雌二醇处理使卵巢中的雌酮水平增加了十倍，而在幽门盲囊中观察到的增加不显著。这可能表明，在体内17β -雌二醇在卵巢中转化为雌酮，但在幽门盲囊中则不会。
