Tourte Monique, Mignotte Françoise, Mounolou Jean-Claude
Laboratoire de Biologie Générale, Bâtiment 400, Université de Paris-Sud, Centre d'Orsay, F-91405 ORSAY Cedex, FRANCE.
Dev Growth Differ. 1981;23(1):9-21. doi: 10.1111/j.1440-169X.1981.00009.x.
The origin of the mitochondrial mass, previously well characterized in Xenupus diplotene oocytes, has been traced up to oogonia by means of electron microscopy. A polarized organization of the oogonia and of the oocytes of the succeeding stages was observed. The mitochondrial cloud was found to be built up in the centriolar region near the site where the chromosomes will be implanted along the nuclear envelope at the "bouquet" stage. Autoradiographic studies of thymidine incorporation into mitochondrial DNA suggest that mitochondrial DNA synthesis is active throughout this early period of oogenesis.
线粒体团块的起源，此前已在非洲爪蟾双线期卵母细胞中得到充分表征，现已通过电子显微镜追溯到卵原细胞。观察到卵原细胞以及后续阶段卵母细胞的极化组织。线粒体云在中心粒区域形成，该区域靠近染色体在“花束”期沿核膜植入的位置。对胸腺嘧啶核苷掺入线粒体DNA的放射自显影研究表明，线粒体DNA合成在卵子发生的这一早期阶段一直活跃。
