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基于心血管重症监护病房重症病例探讨参芪丸内涵及参芪丸在危重症医学中治疗心力衰竭、肾衰竭、心肾综合征及利尿剂抵抗的现代病理生理机制与应用

[Connotation of Shenqi Pills based on severe cases in cardiovascular care unit and modern pathophysiological mechanism and application of Shenqi Pills for heart failure, renal failure, cardiorenal syndrome, and diuretic resistance in critical care medicine].

作者信息

Xiong Xing-Jiang

机构信息

Guang'anmen Hospital, China Academy of Chinese Medical Sciences Beijing 100053, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2023 May;48(10):2565-2582. doi: 10.19540/j.cnki.cjcmm.20230217.501.

Abstract

Shenqi Pills, first recorded in Essentials from the Golden Cabinet(Jin Kui Yao Lue) from ZHANG Zhong-jing in Han dynasty, have the effect of warming and tonifying the kidney Qi and are mainly used for the treatment of insufficiency of kidney Qi and kidney Yang. According to modern medicine, kidney Qi involves heart function, kidney function, immune function, and so on. The clinical indications of Shenqi Pills include kidney deficiency, abnormal fluid, and abnormal urination, and the last one is classified into little urine, much urine, and dysuria. In clinical settings, Shenqi Pills can be applied for the treatment of heart failure, renal failure, cardiorenal syndrome, and diuretic resistance, as well as endocrine, urological, orthopedic, and other chronic degenerative diseases. Shenqi Pills are ideal prescriptions for the weak constitution and emergency treatment. It is of great value and significance to carry out in-depth research on the connotation of the classic articles by integrating TCM and western medicine based on "pathogenesis combined with pathology and drug properties combined with pharmacology".

摘要

肾气丸首载于汉代张仲景的《金匮要略》,具有温补肾气的功效,主要用于治疗肾气不足、肾阳亏虚。现代医学认为,肾气涉及心功能、肾功能、免疫功能等。肾气丸的临床适应证包括肾虚、津液异常、排尿异常,其中排尿异常又分为少尿、多尿、排尿困难。临床应用中,肾气丸可用于治疗心力衰竭、肾衰竭、心肾综合征、利尿剂抵抗,以及内分泌、泌尿、骨科等慢性退行性疾病。肾气丸是体质虚弱者及急救治疗的理想方剂。基于“病机结合病理,药性结合药理”,中西医结合深入研究经典方剂内涵具有重要价值和意义。

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