Department of Urology, Zhujiang Hospital of Southern Medical University, Guangzhou 510282, China.
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2023 Apr 25;52(2):156-161. doi: 10.3724/zdxbyxb-2022-0612.
To investigate the effect of progressive pre-disconnection of urethral mucosal flap during transurethral plasmakinetic enucleation of prostate (TUPEP) on early recovery of urinary continence.
Clinical data of patients with benign prostatic hyperplasia (BPH) admitted in Zhujiang Hospital of Southern Medical University during February and May 2022 were collected. All the patients underwent TUPEP, and the progressive pre-disconnection of urethral mucosal flap was performed in the procedure. The total operation time, enucleation time, postoperative bladder irrigation time and catheter indwelling time were recorded. Urinary continence was evaluated 24 h, 1 week, and 1, 3, 6 months after the removal of urinary catheter.
All surgeries were successfully completed at one time with less intraoperative bleeding, and there were no complications such as rectal injury, bladder injury or perforation of prostate capsule. The total operation time was (62.2±6.5) min, the enucleation time was (42.8±5.2) min, the postoperative hemoglobin decrease by (9.5±4.5) g/L, the postoperative bladder irrigation time was (7.9±1.4) h, and the postoperative catheter indwelling time was 10.0 (9.2, 11.4) h. Only 2 patients (3.6%) had transient urinary incontinence within 24 h after catheter removal. No urinary incontinence occurred at 1 week, and 1, 3, 6 months after operation, and no safety pad was needed. The Qmax at 1 month after operation was 22.3 (20.6, 24.4) mL/s, international prostate symptom scores were 8.0 (7.0, 9.0), 5.0 (4.0, 6.0) and 4.0 (3.0, 4.0) at 1, 3 and 6 months after surgery, and quality of life scores at 1, 3 and 6 months after surgery were 3.0 (2.0, 3.0), 2.0 (1.0, 2.0) and 1.0 (1.0, 2.0), all of these indicators were better than those before surgery (all <0.01).
In the treatment of BPH, the application of progressive pre-disconnection of urethral mucosal flap in TUPEP can completely remove the hyperplastic glands and promote early recovery of postoperative urinary continence with less perioperative bleeding and decreased surgical complications.
探讨经尿道等离子前列腺剜除术(TUPEP)中尿道黏膜瓣逐步预置切断对术后早期控尿恢复的影响。
收集 2022 年 2 月至 5 月在南方医科大学珠江医院接受 TUPEP 治疗的良性前列腺增生(BPH)患者的临床资料。所有患者均行 TUPEP 术,术中行尿道黏膜瓣逐步预置切断。记录手术的总时间、剜除时间、术后膀胱冲洗时间和导尿管留置时间。拔除导尿管后 24 h、1 周、1、3、6 个月评估尿控情况。
所有手术均一次性顺利完成,术中出血量少,无直肠损伤、膀胱损伤或前列腺包膜穿孔等并发症。手术总时间为(62.2±6.5)min,剜除时间为(42.8±5.2)min,术后血红蛋白下降(9.5±4.5)g/L,术后膀胱冲洗时间为(7.9±1.4)h,术后导尿管留置时间为 10.0(9.2,11.4)h。仅 2 例(3.6%)患者在拔除导尿管后 24 h 内出现短暂性尿失禁,术后 1 周、1、3、6 个月均无尿失禁,无需使用尿垫。术后 1 个月最大尿流率为 22.3(20.6,24.4)mL/s,国际前列腺症状评分分别为 8.0(7.0,9.0)、5.0(4.0,6.0)和 4.0(3.0,4.0),术后 1、3、6 个月的生活质量评分分别为 3.0(2.0,3.0)、2.0(1.0,2.0)和 1.0(1.0,2.0),均优于术前(均<0.01)。
在治疗 BPH 时,TUPEP 中应用尿道黏膜瓣逐步预置切断可完全切除增生腺体,减少围手术期出血,降低手术并发症,促进术后早期尿控恢复。