Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon.
Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon.
Int J Gynaecol Obstet. 2023 Jul;162(1):18-23. doi: 10.1002/ijgo.14876. Epub 2023 Jun 7.
The evidence indicates that pregnancy is associated with increased severity of some infectious diseases. Given the high maternal morbidity associated with influenza in pregnancy and the high neonatal morbidity and mortality associated with pertussis, the traditionally two recommended vaccines during pregnancy were those against influenza and Tdap (tetanus toxoid, reduced diphtheria toxoid and acellular pertussis) vaccines. The recent COVID-19 pandemic introduced a third vaccine that after much debate is now recommended for all pregnant women. Other vaccines can be offered based for high-risk pregnant women, and only when the benefits of receiving them outweigh the risks. The soon expected vaccines against group B streptococcus infection and respiratory syncytial virus infection will be a breakthrough in reducing perinatal mortality. In this paper, the recommendations for administration of each vaccine during pregnancy are discussed.
证据表明，妊娠与某些传染病的严重程度增加有关。鉴于流感在妊娠期间给产妇带来的高发病率，以及百日咳给新生儿带来的高发病率和死亡率，传统上在妊娠期间推荐接种两种疫苗，即流感疫苗和 Tdap（破伤风类毒素、无细胞白喉类毒素和百日咳）疫苗。最近的 COVID-19 大流行引入了第三种疫苗，经过广泛讨论，现在建议所有孕妇接种。其他疫苗可以提供给高危孕妇接种，并且只有在接种疫苗的益处大于风险时才可以接种。预计很快将推出针对 B 型链球菌感染和呼吸道合胞病毒感染的疫苗，这将是降低围产期死亡率的一个突破。本文讨论了在妊娠期间接种每种疫苗的建议。
