Pan Zengxiang, Li Xu, Lin Guoqin, Qin Peishan, Piao Zun, Huang Shuang, Wu Wangjiang, Qi Mengke, Zhou Linghong, Xu Yuan
School of Biomedical Engineering, Southern Medical University, Guangzhou, China.
Quant Imaging Med Surg. 2023 Jun 1;13(6):3602-3617. doi: 10.21037/qims-22-1055. Epub 2023 Apr 7.
The energy spectrum is the property of the X-ray tube that describes the energy fluence per unit interval of photon energy. The existing indirect methods for estimating the spectrum ignore the influence caused by the voltage fluctuation of the X-ray tube.
In this work, we propose a method for estimating the X-ray energy spectrum more accurately by including the voltage fluctuation of the X-ray tube. It expresses the spectrum as the weighted summation of a set of model spectra within a certain voltage fluctuation range. The difference between the raw projection and the estimated projection is considered as the objective function for obtaining the corresponding weight of each model spectrum. The equilibrium optimizer (EO) algorithm is used to find the weight combination that minimizes the objective function. Finally, the estimated spectrum is obtained. We refer to the proposed method as the poly-voltage method. The method is mainly aimed at the cone-beam computed tomography (CBCT) system.
The model spectra mixture evaluation and projection evaluation showed that the reference spectrum can be combined by multiple model spectra. They also showed that it is appropriate to choose about 10% of the preset voltage as the voltage range of the model spectra, which can match the reference spectrum and projection quite well. The phantom evaluation showed that the beam-hardening artifact can be corrected using the estimated spectrum via the poly-voltage method, and the poly-voltage method provides not only the accurate reprojection but also an accurate spectrum. The normalized root mean square error (NRMSE) index between the spectrum generated via the poly-voltage method and the reference spectrum could be kept within 3% according to above evaluations. There existed a 1.77% percentage error between the estimated scatter of polymethyl methacrylate (PMMA) phantom using the two spectra generated via the poly-voltage method and the single-voltage method, and it could be considered for scatter simulation.
Our proposed poly-voltage method could estimate the spectrum more accurately for both ideal and more realistic voltage spectra, and it is robust to the different modes of voltage pulse.
能谱是X射线管的一种特性,用于描述光子能量单位间隔内的能量注量。现有的间接估计能谱的方法忽略了X射线管电压波动所造成的影响。
在本研究中,我们提出了一种通过纳入X射线管电压波动来更准确地估计X射线能谱的方法。该方法将能谱表示为在一定电压波动范围内一组模型能谱的加权总和。原始投影与估计投影之间的差异被视为获取每个模型能谱相应权重的目标函数。使用平衡优化器(EO)算法来找到使目标函数最小化的权重组合。最后,得到估计能谱。我们将所提出的方法称为多电压法。该方法主要针对锥束计算机断层扫描(CBCT)系统。
模型能谱混合评估和投影评估表明,参考能谱可由多个模型能谱组合而成。评估还表明,选择约10%的预设电压作为模型能谱的电压范围较为合适,这样能很好地匹配参考能谱和投影。体模评估表明,通过多电压法利用估计能谱可校正硬化伪影,且多电压法不仅能提供准确的重投影,还能提供准确的能谱。根据上述评估,通过多电压法生成的能谱与参考能谱之间的归一化均方根误差(NRMSE)指标可保持在3%以内。使用通过多电压法和单电压法生成的两种能谱对聚甲基丙烯酸甲酯(PMMA)体模的估计散射之间存在1.77%的百分比误差,可用于散射模拟。
我们提出的多电压法对于理想和更实际的电压能谱都能更准确地估计能谱,并且对不同模式的电压脉冲具有鲁棒性。