Carr J M, Kruskall M S, Kaye J A, Robinson S H
Am J Med. 1986 Jun;80(6):1051-4. doi: 10.1016/0002-9343(86)90664-9.
Records of 11 patients with immune thrombocytopenia (idiopathic and quinidine-induced) were evaluated retrospectively for response to platelet transfusion. Good post-transfusion platelet count increments occurred on one or more occasions in seven of the 11 patients, with 13 of 31 platelet transfusions (42 percent) resulting in immediate post-transfusion increments of 20,000/mm3 or more. Next-day platelet counts remained elevated in association with five of these 13 transfusions. This study demonstrates that, contrary to common opinion, platelet transfusions can raise the platelet count in many patients with immune thrombocytopenia, and therefore may be beneficial in actively bleeding or high-risk patients with this disorder.
对11例免疫性血小板减少症（特发性和奎尼丁诱导性）患者的记录进行回顾性评估，以了解其对血小板输注的反应。11例患者中有7例在一次或多次情况下出现了良好的输血后血小板计数增加，31次血小板输注中有13次（42%）导致输血后即刻血小板计数增加20,000/mm³或更多。在这13次输注中有5次，第二天的血小板计数仍保持升高。这项研究表明，与普遍观点相反，血小板输注可使许多免疫性血小板减少症患者的血小板计数升高，因此可能对患有这种疾病的活动性出血或高危患者有益。
