Bamford Centre for Mental Health and Wellbeing, Ulster University, Coleraine, Northern Ireland, United Kingdom.
Administrative Data Research Centre Northern Ireland (ADRC-NI), Coleraine, Northern Ireland, United Kingdom.
PLoS One. 2023 Jun 7;18(6):e0286860. doi: 10.1371/journal.pone.0286860. eCollection 2023.
While evidence has emerged highlighting the potential benefits of the eye as a window to the central nervous system, research on severe mental illness (SMI) and eye health is rare.
We examine the association of SMI with a range of ophthalmic health outcomes, and whether any relationship is modified by age.
We used linked administrative data from general practitioner (GP), hospital and ophthalmic records to examine receipt of any Health and Social Care (HSC) eye-test; and (based on eligibility recorded for a sight test) any glaucoma, any diabetes, and any blindness among the Northern Ireland (NI) hospital population between January 2015 and November 2019 (N = 798,564).
When compared with non-SMI patients, those with SMI recorded a higher prevalence of having had a sight test, diabetes, and blindness. In fully adjusted logistic regression models, higher likelihood of an eye-test and diabetes (OR = 1.71: 95%CI = 1.63, 1.79 and OR = 1.29: 1.19, 1.40 respectively); and lower likelihood of glaucoma remained (OR = 0.69: 0.53, 0.90). Amongst persons with SMI there was evidence that the likelihood of having had an eye-test was lower in the older age-groups.
Our study provides new evidence on ophthalmic health inequalities associated with SMI. While the study has immediate relevance to its NI context, we believe it is generalizable to wider UK health concerns. We emphasize the need for more research of this type, using large linkable electronic administrative databases to further our understanding of both health inequalities associated with SMI and poor eye health, and health outcomes in general.
虽然有证据表明眼睛作为中枢神经系统的窗口具有潜在益处,但针对严重精神疾病 (SMI) 和眼部健康的研究却很少。
我们研究了 SMI 与一系列眼科健康结果的关联,以及这种关联是否会因年龄而改变。
我们使用来自全科医生 (GP)、医院和眼科记录的链接行政数据,来检查北爱尔兰 (NI) 医院人群在 2015 年 1 月至 2019 年 11 月期间是否接受过任何健康和社会保健 (HSC) 眼部检查;以及(根据视力检查的资格记录)是否患有青光眼、任何糖尿病和任何失明(N=798564)。
与非 SMI 患者相比,患有 SMI 的患者接受视力检查、糖尿病和失明的比例更高。在完全调整的逻辑回归模型中,接受眼部检查和糖尿病的可能性更高(OR=1.71:95%CI=1.63,1.79 和 OR=1.29:1.19,1.40);青光眼的可能性仍然较低(OR=0.69:0.53,0.90)。在患有 SMI 的人群中,有证据表明,年龄较大的人群接受眼部检查的可能性较低。
我们的研究提供了与 SMI 相关的眼科健康不平等的新证据。虽然该研究对其 NI 背景具有直接意义,但我们认为它可以推广到更广泛的英国健康问题。我们强调需要进行更多此类研究,使用大型可链接电子行政数据库来进一步了解与 SMI 相关的健康不平等和不良的眼部健康以及一般健康结果。