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新冠肺炎患者 R 波峰时间的预后价值。

Prognostic value of R wave peak time in COVID-19 pneumonia.

机构信息

Hatay Dörtyol State Hospital, 31000, Hatay, Turkey.

Hatay Dörtyol State Hospital, 31000, Hatay, Turkey.

出版信息

J Electrocardiol. 2023 Sep-Oct;80:91-95. doi: 10.1016/j.jelectrocard.2023.05.005. Epub 2023 May 26.

Abstract

BACKGROUND

R wave peak time (RWPT) is also known as intrinsicoid deflection time or ventricular activation time. It shows the conduction time from the endocardium in the ventricle to the epicardium. It provides diagnostic and prognostic information for many cardiovascular diseases, such as RWPT prolongation, left ventricular hypertrophy, volume overload, conduction system abnormalities, and myocardial ischemia. Objectives The aim of this study is to investigate the relationship between COVID-19 mortality and RWPT in superficial ECG.

METHODS

This study retrospectively examined 640 patients diagnosed with COVID-19 and treated in an intensive care unit at a single center between January 2021 and June 2022. All patients included in the study had clinical and radiological characteristics and signs of COVID-19 pneumonia.

RESULTS

640 patients included in the study were divided into 2 groups: surviving and deceased. There were 510 patients in the surviving group and 130 patients in the deceased group. The deceased group was found to be significantly older. The number of patients with COPD was higher in the deceased group. Troponin, lactate dehydrogenase (LDH), C-reactive protein (CRP), D-dimer and T-peak to T-end interval(Tpe) and RWPT were found to be significantly increased in the deceased group. In binary logistic regression analysis; age, COPD, LDH, CRP, troponin, D-dimer, Tpe interval, RWPT were determined as independent risk factors for mortality.

CONCLUSIONS

Prolonged RWPT is useful in risk stratification for COVID-19 pneumonia mortality.

摘要

背景

R 波峰时间(RWPT)也称为固有偏转时间或心室激活时间。它显示了心室内心内膜到心外膜的传导时间。它为许多心血管疾病提供了诊断和预后信息,如 RWPT 延长、左心室肥厚、容量超负荷、传导系统异常和心肌缺血。

目的

本研究旨在探讨体表心电图中 COVID-19 死亡率与 RWPT 的关系。

方法

本研究回顾性分析了 2021 年 1 月至 2022 年 6 月期间在一家中心的重症监护病房接受治疗的 640 例 COVID-19 患者。所有纳入研究的患者均具有 COVID-19 肺炎的临床和影像学特征及征象。

结果

研究纳入的 640 例患者分为存活组和死亡组。存活组 510 例,死亡组 130 例。死亡组年龄明显较大,COPD 患者较多。死亡组肌钙蛋白、乳酸脱氢酶(LDH)、C 反应蛋白(CRP)、D-二聚体和 T 波峰至 T 波末端(Tpe)和 RWPT 明显升高。在二元逻辑回归分析中;年龄、COPD、LDH、CRP、肌钙蛋白、D-二聚体、Tpe 间期、RWPT 被确定为死亡率的独立危险因素。

结论

RWPT 延长对 COVID-19 肺炎死亡率的风险分层有用。

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本文引用的文献

1
Delayed intrinsicoid deflection: Electrocardiographic harbinger of heart disease.延迟性固有偏转:心电图预示心脏病。
Ann Noninvasive Electrocardiol. 2022 May;27(3):e12940. doi: 10.1111/anec.12940. Epub 2022 Feb 17.
2
COVID-19 and arrhythmia: An overview.新型冠状病毒肺炎与心律失常:概述。
J Cardiol. 2022 Apr;79(4):468-475. doi: 10.1016/j.jjcc.2021.11.019. Epub 2021 Dec 1.
10
Cardiac arrhythmias in patients with COVID-19.新型冠状病毒肺炎患者的心律失常
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