Putterman A M
Am J Ophthalmol. 1986 Jul 15;102(1):87-90. doi: 10.1016/0002-9394(86)90214-x.
Sebaceous adenocarcinoma (meibomian gland cancer) can be localized at times to one specific area of the eyelid; at other times, it spreads diffusely by pagetoid invasion throughout the conjunctiva. The pagetoid spread is often impossible to visualize. I used a map biopsy of the conjunctiva to determine the extent of involvement of sebaceous adenocarcinoma in 12 patients. Sixteen conjunctival biopsy specimens were taken from various areas of the palpebral and bulbar conjunctiva. An analysis of these specimens helped to delineate the area of tumor involvement, which aided in determining whether to treat these cases by full-thickness eyelid resection or orbital exenteration.
皮脂腺癌（睑板腺癌）有时可局限于眼睑的一个特定区域；其他时候，它会通过派杰样浸润在整个结膜中弥漫性扩散。派杰样扩散通常无法可视化。我采用结膜地图活检来确定12例皮脂腺癌的累及范围。从睑结膜和球结膜的不同区域采集了16份结膜活检标本。对这些标本的分析有助于勾勒出肿瘤累及区域，这有助于确定是通过全层眼睑切除术还是眼眶内容剜除术来治疗这些病例。
