Aldosari Sultan, Alghamdi Elham A, Alragea Ahmed
Orthopedic Surgery, King Khaled University Hospital, King Saud Medical City, Riyadh, SAU.
Orthopedics, King Saud Medical City, Riyadh, SAU.
Cureus. 2023 Mar 10;15(3):e35979. doi: 10.7759/cureus.35979. eCollection 2023 Mar.
Multiple brown tumors are more common in females and older age groups and an unlikely site is the long bones. We report a case of a 21-year-old male presenting with a pathological fracture at the left neck of the femur. Laboratory investigations showed elevated parathyroid hormone (PTH) and serum calcium levels (PTH-dependent hypercalcemia). A CT scan revealed multiple osteolytic lesions in the pelvis and femurs, and a Tc-99m sestamibi scan showed a solitary parathyroid adenoma. We demonstrate this rare case and illustrate the importance of the consideration of multiple brown tumors in young males presenting with multiple osteolytic lesions at the long bones in the differential diagnosis. Every physician needs to have a high clinical suspicion of primary hyperparathyroidism innovation, in those who present with osteolytic lesions, with respect to the patient's age and gender.
多发性棕色瘤在女性和老年人群中更为常见，长骨较少发生。我们报告一例21岁男性，因左股骨颈病理性骨折就诊。实验室检查显示甲状旁腺激素（PTH）和血清钙水平升高（PTH依赖性高钙血症）。CT扫描显示骨盆和股骨有多个溶骨性病变，Tc-99m甲氧基异丁基异腈扫描显示有一个孤立的甲状旁腺腺瘤。我们展示了这个罕见病例，并说明了在鉴别诊断中考虑年轻男性长骨出现多个溶骨性病变时多发性棕色瘤的重要性。对于出现溶骨性病变的患者，每位医生都需要高度怀疑原发性甲状旁腺功能亢进，这与患者的年龄和性别有关。
