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Introduction: Ongoing clinical challenges in the management of meningiomas and future directions.

作者信息

Wang Justin Z, Nassiri Farshad, Aldape Kenneth, Zadeh Gelareh

机构信息

MacFeeters Hamilton Neuro-Oncology Program, Princess Margaret Cancer Centre, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

出版信息

Neurooncol Adv. 2023 Jun 3;5(Suppl 1):i1-i4. doi: 10.1093/noajnl/vdad030. eCollection 2023 May.

DOI:10.1093/noajnl/vdad030
PMID:37287579
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10243837/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fc2/10243837/32e2b35ffc91/vdad030f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fc2/10243837/32e2b35ffc91/vdad030f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fc2/10243837/32e2b35ffc91/vdad030f0001.jpg

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本文引用的文献

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Clinical implementation of integrated molecular-morphologic risk prediction for meningioma.脑膜瘤综合分子-形态学风险预测的临床实施。
Brain Pathol. 2023 May;33(3):e13132. doi: 10.1111/bpa.13132. Epub 2022 Nov 14.
2
Hypermitotic meningiomas harbor DNA methylation subgroups with distinct biological and clinical features.促纤维增生性脑膜瘤存在具有不同生物学和临床特征的 DNA 甲基化亚群。
Neuro Oncol. 2023 Mar 14;25(3):520-530. doi: 10.1093/neuonc/noac224.
3
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2015-2019.
美国 2015-2019 年确诊的原发性脑和其他中枢神经系统肿瘤 CBTRUS 统计报告。
Neuro Oncol. 2022 Oct 5;24(Suppl 5):v1-v95. doi: 10.1093/neuonc/noac202.
4
Two predominant molecular subtypes of spinal meningioma: thoracic NF2-mutant tumors strongly associated with female sex, and cervical AKT1-mutant tumors originating ventral to the spinal cord.脊髓脑膜瘤的两种主要分子亚型:胸椎部NF2突变型肿瘤与女性密切相关,以及起源于脊髓腹侧的颈椎部AKT1突变型肿瘤。
Acta Neuropathol. 2022 Nov;144(5):1053-1055. doi: 10.1007/s00401-022-02474-9. Epub 2022 Aug 9.
5
Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities.脑膜瘤 DNA 甲基化组鉴定出生物学驱动因素和治疗脆弱性。
Nat Genet. 2022 May;54(5):649-659. doi: 10.1038/s41588-022-01061-8. Epub 2022 May 9.
6
Multiple approaches converge on three biological subtypes of meningioma and extract new insights from published studies.多种方法汇聚于脑膜瘤的三种生物学亚型,并从已发表的研究中提取新的见解。
Sci Adv. 2022 Feb 4;8(5):eabm6247. doi: 10.1126/sciadv.abm6247. Epub 2022 Feb 2.
7
Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated.整合分子形态学脑膜瘤分类:多中心回顾性和前瞻性验证研究。
J Clin Oncol. 2021 Dec 1;39(34):3839-3852. doi: 10.1200/JCO.21.00784. Epub 2021 Oct 7.
8
A molecularly integrated grade for meningioma.一种脑膜瘤的分子整合分级。
Neuro Oncol. 2022 May 4;24(5):796-808. doi: 10.1093/neuonc/noab213.
9
Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas.对小儿脑膜瘤进行分子谱分析显示,其肿瘤特征与成人脑膜瘤明显不同。
Acta Neuropathol. 2021 Nov;142(5):873-886. doi: 10.1007/s00401-021-02351-x. Epub 2021 Sep 8.
10
A clinically applicable integrative molecular classification of meningiomas.一种具有临床应用价值的脑膜瘤综合分子分类方法。
Nature. 2021 Sep;597(7874):119-125. doi: 10.1038/s41586-021-03850-3. Epub 2021 Aug 25.