Giannotti B, De Panfilis G, Manara G C, Cappugi P, Ferrari C
Am J Dermatopathol. 1986 Jun;8(3):220-6. doi: 10.1097/00000372-198606000-00006.
Fifteen biopsies from contact allergic reactions in sensitized patients were taken at different time intervals after application of simple chemicals. Two different procedures for electron microscopy were done. No signs of damage were ever seen in Langerhans cells. The authors are therefore of the opinion that there is still no proof for a target role of Langerhans cells in contact allergic reactions in humans.
在致敏患者中,对15例接触性过敏反应进行活检,于涂抹简单化学物质后的不同时间间隔取材。进行了两种不同的电子显微镜检查程序。在朗格汉斯细胞中从未发现损伤迹象。因此,作者认为,仍没有证据表明朗格汉斯细胞在人类接触性过敏反应中起靶细胞作用。