Department of Anesthesiology and Perioperative Medicine, Tohoku University Graduate School of Medicine, 1-1, Seiryomachi, Aoba-Ku, Sendai, 980-8574, Japan.
Division of Surgical Center and Supply, Sterilization, Tohoku University Hospital, 1-1, Seiryomachi, Aoba-Ku, Sendai, 980-8574, Japan.
J Clin Monit Comput. 2023 Dec;37(6):1513-1519. doi: 10.1007/s10877-023-01038-w. Epub 2023 Jun 8.
The endotracheal tubes (ETTs) used for children have a smaller inner diameter. Accordingly, the resistance across ETT (R) is higher. Theoretically, shortening the ETTs can decrease total airway resistance (R), because R is sum of R and patient's airway resistance. However, the effectiveness of ETT shortening for mechanical ventilation in the clinical setting has not been reported. We assessed the effectiveness of shortening a cuffed ETT for decreasing R, and increasing tidal volume (TV), and estimated the R/R ratio in children. In anesthetized children in a constant pressure-controlled ventilation setting, R and TV were measured with a pneumotachometer before and after shortening a cuffed ETT. In a laboratory experiment, the pressure gradient across the original length, shortened length, and the slip joint alone of the ETT were measured. We then determined the R/R ratio using the above results. The clinical study included 22 children. The median ETT percent shortening was 21.7%. Median R was decreased from 26 to 24 cmHO/L/s, and median TV was increased by 6% after ETT shortening. The laboratory experiment showed that ETT length and the pressure gradient across ETT are linearly related under a certain flow rate, and approximately 40% of the pressure gradient across the ETT at its original length was generated by the slip joint. Median R/R ratio were calculated as 0.69. The effectiveness of ETT shortening on R and TV was very limited, because the resistance of the slip joint was very large.
用于儿童的气管内导管(ETT)的内径较小。因此,ETT 的阻力(R)更高。从理论上讲,缩短 ETT 可以降低总气道阻力(R),因为 R 是 R 和患者气道阻力的总和。然而,在临床环境中,缩短 ETT 对机械通气的有效性尚未得到报道。我们评估了缩短带囊 ETT 以降低 R、增加潮气量(TV)的效果,并估计了儿童的 R/R 比值。在压力控制通气设置下麻醉的儿童中,使用测压计在缩短带囊 ETT 前后测量 R 和 TV。在实验室实验中,测量了 ETT 的原始长度、缩短长度和滑结的单独压力梯度。然后,我们使用上述结果确定了 R/R 比值。临床研究包括 22 名儿童。ETT 的中位数缩短百分比为 21.7%。ETT 缩短后,中位数 R 从 26 降至 24 cmHO/L/s,中位数 TV 增加 6%。实验室实验表明,在一定流量下,ETT 长度与 ETT 上的压力梯度呈线性相关,并且在 ETT 的原始长度上,大约 40%的压力梯度是由滑结产生的。中位数 R/R 比值计算为 0.69。ETT 缩短对 R 和 TV 的影响非常有限,因为滑结的阻力非常大。