• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

经口气管导管短缩对小儿患者压力控制通气时气道阻力和潮气量的影响:一项前瞻性观察研究。

Effectiveness of substantial shortening of the endotracheal tube for decreasing airway resistance and increasing tidal volume during pressure-controlled ventilation in pediatric patients: a prospective observational study.

机构信息

Department of Anesthesiology and Perioperative Medicine, Tohoku University Graduate School of Medicine, 1-1, Seiryomachi, Aoba-Ku, Sendai, 980-8574, Japan.

Division of Surgical Center and Supply, Sterilization, Tohoku University Hospital, 1-1, Seiryomachi, Aoba-Ku, Sendai, 980-8574, Japan.

出版信息

J Clin Monit Comput. 2023 Dec;37(6):1513-1519. doi: 10.1007/s10877-023-01038-w. Epub 2023 Jun 8.

DOI:10.1007/s10877-023-01038-w
PMID:37289350
Abstract

The endotracheal tubes (ETTs) used for children have a smaller inner diameter. Accordingly, the resistance across ETT (R) is higher. Theoretically, shortening the ETTs can decrease total airway resistance (R), because R is sum of R and patient's airway resistance. However, the effectiveness of ETT shortening for mechanical ventilation in the clinical setting has not been reported. We assessed the effectiveness of shortening a cuffed ETT for decreasing R, and increasing tidal volume (TV), and estimated the R/R ratio in children. In anesthetized children in a constant pressure-controlled ventilation setting, R and TV were measured with a pneumotachometer before and after shortening a cuffed ETT. In a laboratory experiment, the pressure gradient across the original length, shortened length, and the slip joint alone of the ETT were measured. We then determined the R/R ratio using the above results. The clinical study included 22 children. The median ETT percent shortening was 21.7%. Median R was decreased from 26 to 24 cmHO/L/s, and median TV was increased by 6% after ETT shortening. The laboratory experiment showed that ETT length and the pressure gradient across ETT are linearly related under a certain flow rate, and approximately 40% of the pressure gradient across the ETT at its original length was generated by the slip joint. Median R/R ratio were calculated as 0.69. The effectiveness of ETT shortening on R and TV was very limited, because the resistance of the slip joint was very large.

摘要

用于儿童的气管内导管(ETT)的内径较小。因此,ETT 的阻力(R)更高。从理论上讲,缩短 ETT 可以降低总气道阻力(R),因为 R 是 R 和患者气道阻力的总和。然而,在临床环境中,缩短 ETT 对机械通气的有效性尚未得到报道。我们评估了缩短带囊 ETT 以降低 R、增加潮气量(TV)的效果,并估计了儿童的 R/R 比值。在压力控制通气设置下麻醉的儿童中,使用测压计在缩短带囊 ETT 前后测量 R 和 TV。在实验室实验中,测量了 ETT 的原始长度、缩短长度和滑结的单独压力梯度。然后,我们使用上述结果确定了 R/R 比值。临床研究包括 22 名儿童。ETT 的中位数缩短百分比为 21.7%。ETT 缩短后,中位数 R 从 26 降至 24 cmHO/L/s,中位数 TV 增加 6%。实验室实验表明,在一定流量下,ETT 长度与 ETT 上的压力梯度呈线性相关,并且在 ETT 的原始长度上,大约 40%的压力梯度是由滑结产生的。中位数 R/R 比值计算为 0.69。ETT 缩短对 R 和 TV 的影响非常有限,因为滑结的阻力非常大。

相似文献

1
Effectiveness of substantial shortening of the endotracheal tube for decreasing airway resistance and increasing tidal volume during pressure-controlled ventilation in pediatric patients: a prospective observational study.经口气管导管短缩对小儿患者压力控制通气时气道阻力和潮气量的影响:一项前瞻性观察研究。
J Clin Monit Comput. 2023 Dec;37(6):1513-1519. doi: 10.1007/s10877-023-01038-w. Epub 2023 Jun 8.
2
Modeling the effect of progressive endotracheal tube occlusion on tidal volume in pressure-control mode.模拟压力控制模式下气管插管逐渐阻塞对潮气量的影响。
Anesth Analg. 2002 Jul;95(1):192-7, table of contents. doi: 10.1097/00000539-200207000-00034.
3
[Distance from the laryngeal mask grip to endotracheal tube tip. A crucial point during fiberoptic intubation in children].[从喉罩手柄到气管导管尖端的距离。儿童纤维支气管镜引导插管中的一个关键点]
Anaesthesist. 2012 Feb;61(2):123-8. doi: 10.1007/s00101-012-1983-7. Epub 2012 Feb 23.
4
The pressure drop across the endotracheal tube in mechanically ventilated pediatric patients.机械通气儿科患者气管内导管的跨壁压差。
Paediatr Anaesth. 2015 Apr;25(4):413-20. doi: 10.1111/pan.12595. Epub 2014 Dec 10.
5
Resistance of pediatric and neonatal endotracheal tubes: influence of flow rate, size, and shape.儿科和新生儿气管内导管的阻力:流速、尺寸和形状的影响。
Crit Care Med. 2000 May;28(5):1595-8. doi: 10.1097/00003246-200005000-00056.
6
Roles of endotracheal tubes and slip joints in respiratory pressure loss: a laboratory study.气管导管和滑动接头在呼吸压力损失中的作用:一项实验室研究。
J Anesth. 2016 Oct;30(5):789-95. doi: 10.1007/s00540-016-2210-5. Epub 2016 Jul 1.
7
Work of breathing for cuffed and uncuffed pediatric endotracheal tubes in an in vitro lung model setting.在体外肺模型环境中,带套囊和不带套囊的儿科气管内导管的呼吸功。
Paediatr Anaesth. 2018 Sep;28(9):780-787. doi: 10.1111/pan.13430. Epub 2018 Jul 13.
8
Detection of endotracheal tube obstruction by analysis of the expiratory flow signal.通过分析呼气流量信号检测气管内导管阻塞
Intensive Care Med. 1998 Nov;24(11):1163-72. doi: 10.1007/s001340050740.
9
Can ventilator settings reduce the negative effects of endotracheal suctioning? Investigations in a mechanical lung model.呼吸机设置能否减轻气管内吸痰的负面影响?在机械肺模型中的研究。
BMC Anesthesiol. 2016 Jun 27;16(1):30. doi: 10.1186/s12871-016-0196-z.
10
Potential inadequacy of automatic tube compensation to decrease inspiratory work load after at least 48 hours of endotracheal tube use in the clinical setting.在临床环境中,至少使用 48 小时的气管内导管后,自动管补偿可能不足以降低吸气功。
Respir Care. 2012 May;57(5):697-703. doi: 10.4187/respcare.01380. Epub 2011 Dec 6.

引用本文的文献

1
Inspiratory effort increases blood volume in the thoracic cavity and decreases end-expiratory lung impedance: a preliminary prospective study.吸气努力增加胸腔内血容量并降低呼气末肺阻抗:一项初步前瞻性研究。
Eur J Appl Physiol. 2025 Apr 3. doi: 10.1007/s00421-025-05767-5.
2
Endotracheal tube, by the venturi effect, reduces the efficacy of increasing inlet pressure in improving pendelluft.气管内管通过文丘里效应降低了增加入口压力提高 Pendelluft 的效果。
PLoS One. 2023 Sep 14;18(9):e0291319. doi: 10.1371/journal.pone.0291319. eCollection 2023.

本文引用的文献

1
Influence of Respiratory Gas Density on Tidal Volume during Mechanical Ventilation: A Laboratory Investigation and Observational Study in Children.机械通气期间呼吸气体密度对儿童潮气量的影响:一项实验室研究与观察性研究
Tohoku J Exp Med. 2022 Apr 19;256(4):271-281. doi: 10.1620/tjem.2022.J003. Epub 2022 Mar 17.
2
Accuracy of Age-Based Formula to Predict the Size and Depth of Cuffed Oral Preformed Endotracheal Tubes in Children Undergoing Tonsillectomy.基于年龄的公式预测扁桃体切除术中儿童带套囊口腔预制气管内导管尺寸和深度的准确性。
Ear Nose Throat J. 2023 Mar;102(3):193-197. doi: 10.1177/0145561320980511. Epub 2021 Feb 9.
3
Accuracy of the Ventilator Automated Displayed Respiratory Mechanics in Passive and Active Breathing Conditions: A Bench Study.
呼吸机自动显示呼吸力学在被动和主动呼吸条件下的准确性:一项台架研究。
Respir Care. 2019 Dec;64(12):1555-1560. doi: 10.4187/respcare.06422. Epub 2019 Jul 16.
4
An in vitro evaluation of the influence of neonatal endotracheal tube diameter and length on the work of breathing.新生儿气管内导管直径和长度对呼吸功影响的体外评估。
Paediatr Anaesth. 2018 May;28(5):458-462. doi: 10.1111/pan.13366. Epub 2018 Apr 6.
5
Roles of endotracheal tubes and slip joints in respiratory pressure loss: a laboratory study.气管导管和滑动接头在呼吸压力损失中的作用:一项实验室研究。
J Anesth. 2016 Oct;30(5):789-95. doi: 10.1007/s00540-016-2210-5. Epub 2016 Jul 1.
6
Reduction of Endotracheal Tube Connector Dead Space Improves Ventilation: A Bench Test on a Model Lung Simulating an Extremely Low Birth Weight Neonate.减少气管导管接头死腔可改善通气:对模拟极低出生体重新生儿的模型肺进行的台架试验
Respir Care. 2016 Feb;61(2):155-61. doi: 10.4187/respcare.04076. Epub 2015 Nov 17.
7
The pressure drop across the endotracheal tube in mechanically ventilated pediatric patients.机械通气儿科患者气管内导管的跨壁压差。
Paediatr Anaesth. 2015 Apr;25(4):413-20. doi: 10.1111/pan.12595. Epub 2014 Dec 10.
8
Cut tracheal tube and GlideRite Rigid Stylet.切割气管导管和GlideRite硬质探条。
Br J Anaesth. 2014 Sep;113(3):517-8. doi: 10.1093/bja/aeu279.
9
Higher fraction of inspired oxygen in anesthesia induction does not affect functional residual capacity reduction after intubation: a comparative study of higher and lower oxygen concentration.麻醉诱导时吸入氧分数较高不会影响插管后功能残气量减少:高浓度与低浓度氧气的比较研究。
J Anesth. 2013 Jun;27(3):385-9. doi: 10.1007/s00540-012-1547-7. Epub 2013 Jan 18.
10
Estimation of tracheal pressure and imposed expiratory work of breathing by the endotracheal tube, heat and moisture exchanger, and ventilator during mechanical ventilation.在机械通气期间,通过气管内导管、热和湿交换器以及呼吸机来估计气管压力和呼吸所施加的呼气功。
Respir Care. 2013 Jul;58(7):1157-69. doi: 10.4187/respcare.01698. Epub 2012 Dec 4.