School of Nursing, Fudan University, Shanghai, China; Huashan Hospital affiliated to Fudan University, Shanghai, China.
Department of Nursing, Beijing Ji Shui Tan Hospital, Beijing, China.
Geriatr Nurs. 2023 Jul-Aug;52:106-114. doi: 10.1016/j.gerinurse.2023.05.009. Epub 2023 Jun 6.
Diuretic intake increases the risk of falling. However, previous studies have shown inconsistent correlations between diuretics and falls. This meta-analysis aimed to provide a comprehensive overview of the relationship between diuretic use and risk of falls in older adult individuals.
Six databases (Cochrane Library, PubMed, Medline, CINAHL, Web of Science, and EMBASE) were searched from their inception to November 9, 2022. The risk of bias was independently evaluated using the Newcastle-Ottawa Quality Assessment Scale. A comprehensive meta-analysis was used to analyze the eligible studies.
Fifteen articles were analyzed. Studies have shown that diuretics can increase the risk of falls in older adult individuals. The probability of falls in older adult individuals who used diuretics was 1.185 times higher than in those who did not take diuretics.
Diuretics were significantly associated with an increased risk of falls.
利尿剂的摄入会增加跌倒的风险。然而，先前的研究表明利尿剂与跌倒之间的相关性并不一致。本荟萃分析旨在全面概述老年人群中利尿剂使用与跌倒风险之间的关系。
从建库到 2022 年 11 月 9 日，检索了六个数据库（Cochrane Library、PubMed、Medline、CINAHL、Web of Science 和 EMBASE）。使用纽卡斯尔-渥太华质量评估量表独立评估偏倚风险。使用综合荟萃分析对合格研究进行分析。
分析了 15 篇文章。研究表明，利尿剂会增加老年人群跌倒的风险。使用利尿剂的老年人群发生跌倒的概率是未使用利尿剂的 1.185 倍。
利尿剂与跌倒风险显著相关。
