State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China.
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China; School of Environment, Hangzhou Institute for Advanced Study, UCAS, Hangzhou, 310024, China.
Talanta. 2023 Nov 1;264:124750. doi: 10.1016/j.talanta.2023.124750. Epub 2023 Jun 1.
Tetrabromobisphenol A (TBBPA) and its derivatives are regarded as new contaminants, raising much attention on their environmental occurrence and fates. However, the sensitive detection of TBBPA and its main derivatives is still a great challenge. This study investigated a sensitive method for simultaneous detection of TBBPA and its ten derivatives using high-performance liquid chromatography coupled with triple quadrupole mass spectrometry (HPLC-MS/MS) with atmospheric pressure chemical ionization (APCI) source. The method exhibited much better performance than previously reported methods. Furthermore, it was successfully applied in determining complicated environmental samples, including sewage sludge, river water and vegetable samples with concentration range from undetected (n.d.) to 25.8 ng g dry weight (dw). For sewage sludge, river water and vegetable samples, the spiking recoveries of TBBPA and its derivatives ranged from 69.6 ± 7.0% to 86.1 ± 12.9%, 69.5 ± 13.9% to 87.5 ± 6.6%, and 68.2 ± 5.6% to 80.2 ± 8.3%, respectively; the accuracy ranged from 94.9 ± 4.6% to 113 ± 5%, 91.9 ± 10.9% to 112 ± 7%, and 92.1 ± 5.1% to 106 ± 6%, and the method quantitative limits ranged from 0.00801 to 0.224 ng g dw, 0.0104-0.253 ng L, and 0.00524-0.152 ng g dw, respectively. Moreover, the present manuscript describes for the first time the simultaneous detection of TBBPA and ten derivatives from various environmental samples, providing fundamental work for further research on their environmental occurrences, behaviors and fates.
四溴双酚 A（TBBPA）及其衍生物被认为是新型污染物，其环境存在和归宿引起了广泛关注。然而，TBBPA 及其主要衍生物的灵敏检测仍然是一个巨大的挑战。本研究采用高效液相色谱-三重四极杆质谱联用（HPLC-MS/MS）结合大气压化学电离（APCI）源，建立了同时检测 TBBPA 及其十种衍生物的灵敏方法。该方法的性能明显优于之前报道的方法。此外，该方法还成功应用于复杂环境样品的测定，包括污水污泥、河水和蔬菜样品，浓度范围为未检出（n.d.）至 25.8ng/g 干重（dw）。对于污水污泥、河水和蔬菜样品，TBBPA 及其衍生物的加标回收率范围为 69.6±7.0%至 86.1±12.9%、69.5±13.9%至 87.5±6.6%和 68.2±5.6%至 80.2±8.3%；准确度范围为 94.9±4.6%至 113±5%、91.9±10.9%至 112±7%和 92.1±5.1%至 106±6%；方法定量限范围为 0.00801 至 0.224ng/g dw、0.0104 至 0.253ng/L 和 0.00524 至 0.152ng/g dw。此外，本研究首次描述了从各种环境样品中同时检测 TBBPA 和十种衍生物的方法，为进一步研究它们在环境中的存在、行为和归宿提供了基础工作。
