一种新型沙鼠相关哺乳动物正呼肠孤病毒（沙粒病毒科）在欧洲刺猬（Erinaceus roumanicus）中。
A novel mammarenavirus (family Arenaviridae) in hedgehogs (Erinaceus roumanicus) in Europe.
机构信息
Department of Medical Microbiology and Immunology, Medical School, University of Pécs, Szigeti út 12., 7624, Pécs, Hungary.
Hungarian Nature Research Society, Ajka, Hungary.
出版信息
Arch Virol. 2023 Jun 8;168(7):174. doi: 10.1007/s00705-023-05804-8.
In this study, a novel mammarenavirus (family Arenaviridae) was identified in a hedgehog (family Erinaceidae) in Hungary and genetically characterized. Mecsek Mountains virus (MEMV, OP191655, OP191656) was detected in nine (45%) out of 20 faecal specimens collected from a Northern white-breasted hedgehog (Erinaceus roumanicus). The L-segment proteins (RdRp and Z) and S-segment proteins (NP and GPC) of MEMV had 67.5%/70% and 74.6%/65.6% amino acid sequence identity, respectively, to the corresponding proteins of Alxa virus (species Mammarenavirus alashanense) identified recently in an anal swab from a three-toed jerboa (Dipus sagitta) in China. MEMV is the second known arenavirus endemic in Europe.
在这项研究中，匈牙利的一只刺猬（猬科）中发现了一种新型沙粒病毒（沙粒病毒科），并对其进行了基因特征分析。在从 20 份来自北方白刺猬（Erinaceus roumanicus）的粪便样本中，检测到了 Mecsek Mountains 病毒（MEMV，OP191655，OP191656）。MEMV 的 L 段蛋白（RdRp 和 Z）和 S 段蛋白（NP 和 GPC）与最近在中国从一只三趾跳鼠（Dipus sagitta）的肛拭子中鉴定出的阿尔山病毒（Mammarenavirus alashanense 种）的相应蛋白分别具有 67.5%/70%和 74.6%/65.6%的氨基酸序列同一性。MEMV 是在欧洲发现的第二种已知的沙粒病毒。
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