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经皮短节段椎弓根螺钉固定术不融合治疗胸腰椎爆裂骨折的疗效:与后路短节段椎弓根螺钉固定加侧方融合术的对比研究

Percutaneous short-segment pedicle screw placement without fusion in the treatment of thoracolumbar burst fractures: is it effective?: comparative study with open short-segment pedicle screw fixation with posterolateral fusion.

机构信息

Department of Neurosurgery, Chonnam National University Medical School & Research Institute of Medical Sciences, Gwangju, South Korea.

出版信息

Acta Neurochir (Wien). 2013 Dec;155(12):2305-12; discussion 2312. doi: 10.1007/s00701-013-1859-x. Epub 2013 Sep 10.

Abstract

BACKGROUND

Since introduction of the pedicle screw-rod system, short-segment pedicle screw fixation has been widely adopted for thoracolumbar burst fractures (TLBF). Recently, the percutaneous pedicle screw fixation (PPSF) systems have been introduced in spinal surgery; and it has become a popularly used method for the treatment of degenerative spinal disease. However, there are few clinical reports concerning the efficacy of PPSF without fusion in treatment of TLBF. The purpose of this study was to determine the efficacy and safety of short-segment PPSF without fusion in comparison to open short-segment pedicle screw fixation with bony fusion in treatment of TLBF.

METHODS

This study included 59 patients, who underwent either percutaneous (n = 32) or open (n = 27) short-segment pedicle screw fixation for stabilization of TLBF between December 2003 and October 2009. Radiographs were obtained before surgery, immediately after surgery, and at the final follow-up for assessment of the restoration of the spinal column. For radiologic parameters, Cobb angle, vertebral wedge angle, and vertebral body compression ratio were assessed on a lateral thoracolumbar radiograph. For patient's pain and functional assessment, the visual analogue scale (VAS), the Frankel grading system, and Low Back Outcome Score (LBOS) were measured. Operation time, and the amount of intraoperative bleeding loss were also evaluated.

FINDINGS

In both groups, regional kyphosis (Cobb angle) showed significant improvement immediately after surgery, which was maintained until the last follow up, compared with preoperative regional kyphosis. Postoperative correction loss showed no significant difference between the two groups at the final follow-up. In the percutaneous surgery group, there were significant declines of intraoperative blood loss, and operation time compared with the open surgery group. Clinical results showed that the percutaneous surgery group had a lower VAS score and a better LBOS at three months and six months after surgery; however, the outcomes were similar in the last follow-up.

CONCLUSIONS

Both open and percutaneous short-segment pedicle fixation were safe and effective for treatment of TLBF. Although both groups showed favorable clinical and radiologic outcomes at the final follow-up, PPSF without bone graft provided earlier pain relief and functional improvement, compared with open TPSF with posterolateral bony fusion. Despite several shortcomings in this study, the result suggests that ongoing use of PPSF is recommended for the treatment of TLBF.

摘要

背景

自从椎弓根螺钉-棒系统问世以来,短节段椎弓根螺钉固定已广泛应用于胸腰椎爆裂性骨折(TLBF)。最近,经皮椎弓根螺钉固定(PPSF)系统已被引入脊柱外科;并且已成为治疗退行性脊柱疾病的常用方法。然而,关于不融合的经皮短节段螺钉固定治疗 TLBF 的疗效的临床报道很少。本研究的目的是确定不融合的短节段 PPSF 与开放短节段椎弓根螺钉固定加骨融合治疗 TLBF 的疗效和安全性。

方法

本研究纳入 2003 年 12 月至 2009 年 10 月期间接受经皮(n = 32)或开放(n = 27)短节段椎弓根螺钉固定治疗 TLBF 的 59 例患者。在术前、术后即刻和末次随访时拍摄侧位胸腰椎 X 线片评估脊柱的恢复情况。对于影像学参数,采用 Cobb 角、椎体楔形角和椎体压缩比进行评估。对于患者的疼痛和功能评估,采用视觉模拟评分(VAS)、Frankel 分级系统和下腰痛结局评分(LBOS)进行测量。还评估了手术时间和术中出血量。

结果

两组患者术后即刻区域后凸角(Cobb 角)均有显著改善,且与术前区域后凸角相比,直至末次随访时均保持稳定。两组末次随访时的术后矫正丢失无显著差异。与开放手术组相比,经皮手术组术中出血量和手术时间明显减少。临床结果表明,术后 3 个月和 6 个月,经皮手术组的 VAS 评分和 LBOS 较低;然而,末次随访时结果相似。

结论

开放和经皮短节段椎弓根固定治疗 TLBF 均安全有效。尽管两组患者在末次随访时均获得了良好的临床和影像学结果,但与开放 TPSF 加后外侧骨融合相比,PPSF 不植骨可更早缓解疼痛和改善功能。尽管本研究存在一些局限性,但结果表明,PPSF 可推荐用于 TLBF 的治疗。

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