Small Animal Teaching Hospital, School of Veterinary Science, University of Liverpool, Neston, UK.
Vets Now Glasgow Hospital, Glasgow, UK.
Vet Rec. 2023 Sep 20;193(6):e2787. doi: 10.1002/vetr.2787. Epub 2023 Mar 12.
This study aimed to identify complications associated with cerebrospinal fluid (CSF) collection in dogs.
This was a prospective, observational multicentre study using data collected from 102 dogs undergoing CSF collection for the investigation of neurological disease. CSF was collected from the cerebellomedullary cistern (CMC), lumbar subarachnoid space (LSAS) or both sites. Pre-, intra- and postprocedural data were collected. Descriptive statistics were performed to outline complications associated with CSF collection.
CSF sampling was attempted on 108 occasions, and CSF was acquired on 100 occasions (92.6%). Collection from the CMC was more likely to be successful than that from the LSAS. No dogs exhibited neurologic deterioration following CSF collection. There was no significant difference between pre- and post-CSF collection short-form Glasgow composite measure pain scores in ambulatory dogs (p = 0.13).
The scarcity of complications limited the ability to quantify the incidence of some potential complications reported elsewhere.
Our results may be used to inform clinicians and owners that CSF sampling is associated with a low frequency of complications when performed by trained personnel.
本研究旨在确定与犬脑脊液（CSF）采集相关的并发症。
这是一项前瞻性、观察性的多中心研究，使用了 102 只因神经疾病而接受 CSF 采集的犬的数据。CSF 从小脑延髓池（CMC）、腰椎蛛网膜下腔（LSAS）或两个部位采集。采集前、采集中和采集后收集数据。采用描述性统计方法总结与 CSF 采集相关的并发症。
共尝试了 108 次 CSF 采样，成功采集了 100 次（92.6%）。从 CMC 采集 CSF 比从 LSAS 采集 CSF 更有可能成功。在接受 CSF 采集后，没有犬出现神经功能恶化。在活动犬中，CSF 采集前后短格式格拉斯哥复合测量疼痛评分无显著差异（p = 0.13）。
并发症的罕见性限制了对其他地方报告的一些潜在并发症发生率进行量化的能力。
我们的结果可用于告知临床医生和犬主，在经过培训的人员进行操作时，CSF 采样与低频率的并发症相关。
