一种短杆菌属细菌中腈水合酶合成的调控
Regulation of nitrile-hydratase synthesis in a Brevibacterium species.
作者信息
Tourneix D, Thiéry A, Maestracci M, Arnaud A, Galzy P
出版信息
Antonie Van Leeuwenhoek. 1986;52(2):173-82. doi: 10.1007/BF00429321.
PMID:3729377
Abstract
The regulation of nitrile-hydratase biosynthese was studied in Brevibacterium sp R 312. Enzyme biosynthesis was not influenced by any carbon and nitrogen source used in the growth medium. It was, however, repressed by amide and amide analogues. Acetamide repressed nitrile-hydratase biosynthesis and induced the wide-spectrum amidase. Therefore, it appeared reasonable to hypothesize a single repressor gene for the nitrile-hydratase/wide-spectrum amidase system.
摘要
对短杆菌属R 312中的腈水合酶生物合成调控进行了研究。酶的生物合成不受生长培养基中使用的任何碳源和氮源的影响。然而，它受到酰胺和酰胺类似物的抑制。乙酰胺抑制腈水合酶的生物合成并诱导广谱酰胺酶。因此，假设腈水合酶/广谱酰胺酶系统存在一个单一的阻遏基因似乎是合理的。
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