Constantin Adrian, Constantin Roxana, Achim Florin, Socea Bogdan, Predescu Dragos
Department of Esophageal and General Surgery, Sf. Maria Clinical Hospital Bucharest, 011192 Bucharest, Romania.
Faculty of Medicine, Carol Davila University of Medicine and Pharmacy Bucharest, 050474 Bucharest, Romania.
Diagnostics (Basel). 2023 May 29;13(11):1909. doi: 10.3390/diagnostics13111909.
Cases of digestive cancers diagnosed during pregnancy are rare. The increasing prevalence of pregnancy in women aged 30-39 years (and not exceptionally 40-49 years) could explain the frequent co-occurrence of cancers and pregnancy. The diagnosis of digestive cancers in pregnancy is difficult due to the overlap between neoplasm symptomatology and the clinical picture of pregnancy. A paraclinical evaluation may also be difficult depending on the trimester of the pregnancy. Diagnosis is also delayed by practitioners' hesitation to use invasive investigations (imaging, endoscopy, etc.) due to fetal safety concerns. Therefore, digestive cancers are often diagnosed during pregnancy in advanced stages, where complications such as occlusions, perforations, and cachexia have already arisen. In this review, we highlight the epidemiology, clinical aspects, paraclinical evaluation, and particularities of the diagnosis and treatment of gastric cancer during pregnancy.
孕期诊断出消化系统癌症的病例很罕见。30至39岁(甚至40至49岁也并不罕见)女性怀孕率的上升,可能解释了癌症与怀孕常同时出现的情况。由于肿瘤症状学与孕期临床表现重叠,孕期消化系统癌症的诊断很困难。根据孕期不同阶段,辅助临床评估也可能存在困难。由于担心胎儿安全,医生对使用侵入性检查(影像学、内窥镜检查等)犹豫不决,这也导致诊断延迟。因此,消化系统癌症在孕期往往在晚期才被诊断出来,此时诸如梗阻、穿孔和恶病质等并发症已经出现。在本综述中,我们重点介绍了孕期胃癌的流行病学、临床情况、辅助临床评估以及诊断和治疗的特殊性。