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Machine Learning Models for the Identification of Prognostic and Predictive Cancer Biomarkers: A Systematic Review.机器学习模型在预后和预测性癌症生物标志物识别中的应用:系统评价。
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2
Comutations and KRASG12C Inhibitor Efficacy in Advanced NSCLC.晚期 NSCLC 中的联合治疗和 KRASG12C 抑制剂疗效。
Cancer Discov. 2023 Jul 7;13(7):1556-1571. doi: 10.1158/2159-8290.CD-22-1420.
3
Co-Mutation Status Association with Clinical Outcomes in Patients with -Mutant Non-Small Cell Lung Cancer.共同突变状态与EGFR突变型非小细胞肺癌患者临床结局的关联
Cancers (Basel). 2022 Dec 12;14(24):6127. doi: 10.3390/cancers14246127.
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Fatty Acid Synthase Mutations Predict Favorable Immune Checkpoint Inhibitor Outcome and Response in Melanoma and Non-Small Cell Lung Cancer Patients.脂肪酸合酶突变预示黑色素瘤和非小细胞肺癌患者免疫检查点抑制剂治疗的良好结局和反应
Cancers (Basel). 2022 Nov 17;14(22):5638. doi: 10.3390/cancers14225638.
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Efficacy and Safety of Epidermal Growth Factor Receptor (EGFR)-Tyrosine Kinase Inhibitor Combination Therapy as First-Line Treatment for Patients with Advanced -Mutated, Non-Small Cell Lung Cancer: A Systematic Review and Bayesian Network Meta-Analysis.表皮生长因子受体(EGFR)-酪氨酸激酶抑制剂联合疗法作为晚期突变型非小细胞肺癌患者一线治疗的疗效和安全性:一项系统评价和贝叶斯网络荟萃分析
Cancers (Basel). 2022 Oct 6;14(19):4894. doi: 10.3390/cancers14194894.
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A Machine Learning-Based Predictive Model of Epidermal Growth Factor Mutations in Lung Adenocarcinomas.一种基于机器学习的肺腺癌表皮生长因子突变预测模型。
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8
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Mutation Association with Immune Checkpoint Inhibitor Outcome in Melanoma and Non-Small Cell Lung Cancer.黑色素瘤和非小细胞肺癌中与免疫检查点抑制剂疗效相关的突变
Cancers (Basel). 2022 Jul 19;14(14):3495. doi: 10.3390/cancers14143495.

肺癌可操作突变的新进展

New Actions on Actionable Mutations in Lung Cancers.

作者信息

Le Xiuning, Elamin Yasir Y, Zhang Jianjun

机构信息

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

出版信息

Cancers (Basel). 2023 May 26;15(11):2917. doi: 10.3390/cancers15112917.

DOI:10.3390/cancers15112917
PMID:37296880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10252025/
Abstract

Actionable mutations refer to DNA alterations that, if detected, would be expected to affect patients' response to treatments [...].

摘要

可操作的突变是指那些一旦被检测到,预计会影响患者对治疗反应的DNA改变[……]。