Tran Hung Do, Hung Tran Thanh, Thuy Phuong Tran Hoang, Tam Le Thanh, Tran Hung Gia, Le Phuoc Huu
Faculty of Nursing and Medical Technology, Can Tho University of Medicine and Pharmacy, 179 Nguyen Van Cu Street, Can Tho City 94000, Vietnam.
Faculty of Medicine, Can Tho University of Medicine and Pharmacy, 179 Nguyen Van Cu Street, Can Tho City 94000, Vietnam.
Healthcare (Basel). 2023 Jun 2;11(11):1632. doi: 10.3390/healthcare11111632.
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, is among the top global health crises. As confirmed by the Vietnam Ministry of Health on 25th January 2023, Vietnam had a cumulative total of more than 11.52 million COVID-19 patients, including 10.61 million recoveries and 43,186 deaths.
This study aimed to describe the clinical and subclinical characteristics, treatment progress, and outcomes of 310 cases of SARS-CoV-2 infection.
A total of 310 patients with medical records of SARS-CoV-2 were admitted to Can Tho City Hospital of Tuberculosis and Lung Diseases, Can Tho city, Vietnam, between July 2021 and December 2021. Demographic and clinical data, including laboratory examinations, of all the patients were collected and analyzed.
The median duration of hospital stay was 16.4 ± 5.3 days. There were 243 (78.4%) patients with clinical symptoms of COVID-19 and 67 (21.6%) patients without clinical symptoms. The common symptoms included cough (71.6% of 310 patients), fever (35.4%), shortness of breath (22.6%), sore throat (21.4%), loss of smell/taste (15.6%), and diarrhea (14.4%). Regarding treatment outcomes, 92.3% of the patients were discharged from the hospital, 1.9% of the patients suffered a more severe illness and were transferred to a higher-level hospital, and 5.8% of the patients died. The RT-PCR results were negative in 55.2% of the patients, and 37.1% of the patients had positive RT-PCR results with Ct values of >30 on the discharge/transfer day. Multivariate logistic regression analyses showed that comorbidity and decreased blood pH were statistically significantly related to the treatment outcomes of the patients with COVID-19 ( < 0.05).
This study provides useful information (i.e., the clinical characteristics and treatment outcomes) on the COVID-19 pandemic in Vietnam during its biggest outbreak; the information may be used for reference and for making improvements in the handling of future health crises.
2019冠状病毒病（COVID-19）由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染引起，是全球最严重的健康危机之一。越南卫生部于2023年1月25日确认，越南累计有超过1152万例COVID-19患者，其中1061万例康复，43186例死亡。
本研究旨在描述310例SARS-CoV-2感染病例的临床和亚临床特征、治疗进展及预后。
2021年7月至2021年12月期间，越南芹苴市结核病和肺病医院共收治了310例有SARS-CoV-2病历的患者。收集并分析了所有患者的人口统计学和临床数据，包括实验室检查结果。
住院时间中位数为16.4±5.3天。有243例（78.4%）患者出现COVID-19临床症状，67例（21.6%）患者无临床症状。常见症状包括咳嗽（310例患者中的71.6%）、发热（35.4%）、呼吸急促（22.6%）、咽痛（21.4%）、嗅觉/味觉丧失（15.6%）和腹泻（14.4%）。关于治疗结果，92.3%的患者出院，1.9%的患者病情加重并转至上级医院，5.8%的患者死亡。55.2%的患者RT-PCR结果为阴性，37.1%的患者在出院/转院当天RT-PCR结果为阳性，Ct值>30。多因素逻辑回归分析显示，合并症和血液pH值降低与COVID-19患者的治疗结果在统计学上显著相关（<0.05）。
本研究提供了越南COVID-19大流行最大规模暴发期间的有用信息（即临床特征和治疗结果）；这些信息可用于参考以及改进未来健康危机的应对措施。
