Matko Karin, Burzynski Meike, Pilhatsch Maximilian, Brinkhaus Benno, Michalsen Andreas, Bringmann Holger C
Department of Psychology, Chemnitz University of Technology, 09120 Chemnitz, Germany.
Department of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01069 Dresden, Germany.
J Clin Med. 2023 May 31;12(11):3778. doi: 10.3390/jcm12113778.
Chronic pain is a growing worldwide health problem and complementary and integrative therapy options are becoming increasingly important. Multi-component yoga interventions represent such an integrative therapy approach with a promising body of evidence.
The present study employed an experimental single-case multiple-baseline design. It investigated the effects of an 8-week yoga-based mind-body intervention, Meditation-Based Lifestyle Modification (MBLM), in the treatment of chronic pain. The main outcomes were pain intensity (BPI-sf), quality of life (WHO-5), and pain self-efficacy (PSEQ).
Twenty-two patients with chronic pain (back pain, fibromyalgia, or migraines) participated in the study and 17 women completed the intervention. MBLM proved to be an effective intervention for a large proportion of the participants. The largest effects were found for pain self-efficacy (TAU- = 0.35), followed by average pain intensity (TAU- = 0.21), quality of life (TAU- = 0.23), and most severe pain (TAU- = 0.14). However, the participants varied in their responses to the treatment.
The present results point to relevant clinical effects of MBLM for the multifactorial conditions of chronic pain. Future controlled clinical studies should investigate its usefulness and safety with larger samples. The ethical and philosophical aspects of yoga should be further explored to verify their therapeutic utility.
慢性疼痛是一个在全球范围内日益严重的健康问题，补充和综合治疗方案正变得越来越重要。多成分瑜伽干预就是这样一种有大量证据支持的综合治疗方法。
本研究采用实验性单病例多基线设计。它调查了一种为期8周的基于瑜伽的身心干预——基于冥想的生活方式改变（MBLM）对慢性疼痛治疗的效果。主要结果指标为疼痛强度（简明疼痛量表简表）、生活质量（世界卫生组织-5）和疼痛自我效能感（疼痛自我效能量表）。
22名慢性疼痛患者（背痛、纤维肌痛或偏头痛）参与了研究，17名女性完成了干预。MBLM被证明对大部分参与者是一种有效的干预。在疼痛自我效能感方面发现了最大的效果（治疗后减基线差值=0.35），其次是平均疼痛强度（治疗后减基线差值=0.21）、生活质量（治疗后减基线差值=0.23）和最严重疼痛（治疗后减基线差值=0.14）。然而，参与者对治疗的反应各不相同。
目前的结果表明MBLM对慢性疼痛的多因素状况具有相关临床效果。未来的对照临床研究应以更大样本量调查其有效性和安全性。应进一步探索瑜伽的伦理和哲学方面，以验证其治疗效用。
