National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
State Key Laboratory of Wheat and Maize Crop Science, College of Agronomy, Henan Agricultural University, Zhengzhou 450002, China.
Int J Mol Sci. 2023 May 27;24(11):9349. doi: 10.3390/ijms24119349.
Transposons (TEs) account for more than 80% of the wheat genome, the highest among all known crop species. They play an important role in shaping the elaborate genomic landscape, which is the key to the speciation of wheat. In this study, we analyzed the association between TEs, chromatin states, and chromatin accessibility in , the D genome donor of bread wheat. We found that TEs contributed to the complex but orderly epigenetic landscape as chromatin states showed diverse distributions on TEs of different orders or superfamilies. TEs also contributed to the chromatin state and openness of potential regulatory elements, affecting the expression of TE-related genes. Some TE superfamilies, such as hAT-Ac, carry active/open chromatin regions. In addition, the histone mark H3K9ac was found to be associated with the accessibility shaped by TEs. These results suggest the role of diversiform TEs in shaping the epigenetic landscape and in gene expression regulation in . This has positive implications for understanding the transposon roles in or the wheat D genome.
转座子 (TEs) 占小麦基因组的 80%以上，在所有已知作物物种中占比最高。它们在塑造精细的基因组景观方面发挥着重要作用，这是小麦物种形成的关键。在这项研究中，我们分析了 , 即面包小麦 D 基因组供体中 TEs、染色质状态和染色质可及性之间的关联。我们发现 TEs 作为不同阶或超家族的 TE 上显示出不同的分布，有助于复杂但有序的表观遗传景观。TEs 还影响与 TE 相关基因的表达，影响潜在调控元件的染色质状态和开放性。一些 TE 超家族，如 hAT-Ac，携带活性/开放染色质区域。此外，组蛋白标记 H3K9ac 与由 TEs 形成的可及性相关。这些结果表明，多样化的 TEs 在塑造 , 或小麦 D 基因组中的表观遗传景观和基因表达调控方面发挥作用。这对理解转座子在 或小麦 D 基因组中的作用具有积极意义。
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