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用异克舒令预防皮瓣坏死及治疗失活皮瓣的实验研究。

Experimental work with isoxuprine for prevention of skin flap necrosis and for treatment of the failing flap.

作者信息

Finseth F, Adelberg M G

出版信息

Plast Reconstr Surg. 1979 Jan;63(1):94-100. doi: 10.1097/00006534-197901000-00015.

DOI:10.1097/00006534-197901000-00015
PMID:372989
Abstract

The administration of isoxuprine intraperitoneally resulted in the complete survival of abdominal island skin flaps in rats that otherwise underwent a standard pattern of necrosis. The drug was effective when administered for two weeks before and one week after raising the flap, or when administered afterwards alone. The mechanisms of its action were investigated and are described.

摘要

腹腔注射异克舒令可使原本会发生标准坏死模式的大鼠腹部岛状皮瓣完全存活。在掀起皮瓣前两周和掀起后一周给药,或仅在掀起后给药,该药均有效。对其作用机制进行了研究并予以描述。

相似文献

1
Experimental work with isoxuprine for prevention of skin flap necrosis and for treatment of the failing flap.用异克舒令预防皮瓣坏死及治疗失活皮瓣的实验研究。
Plast Reconstr Surg. 1979 Jan;63(1):94-100. doi: 10.1097/00006534-197901000-00015.
2
Prevention of skin flap necrosis by a course of treatment with vasodilator drugs.通过使用血管扩张药物进行一个疗程的治疗来预防皮瓣坏死。
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Clinical salvage of three failing skin flaps by treatment with a vasodilator drug.通过使用血管扩张药物治疗对三个濒临坏死的皮瓣进行临床挽救。
Plast Reconstr Surg. 1979 Mar;63(3):304-8. doi: 10.1097/00006534-197903000-00002.
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Drug treatment and flap survival.药物治疗与皮瓣存活
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A study of the treatment time necessary for the vasodilator drug isoxsuprine to prevent necrosis in a skin flap.一项关于血管扩张剂药物异舒普林预防皮瓣坏死所需治疗时间的研究。
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Clinical salvage of three failing skin flaps by treatment with a vasodilator drug (by Frederick Finseth, M.D.). Commentary.用血管扩张剂药物治疗挽救三个失败皮瓣的临床研究(作者:弗雷德里克·芬塞思医学博士)。评论
Plast Reconstr Surg. 1979 Apr;63(4):564-5.

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West J Med. 1980 Oct;133(4):324.
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