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生物活性芪类衍生物的分析、性质与应用。

Analytics, Properties and Applications of Biologically Active Stilbene Derivatives.

机构信息

Faculty of Sciences, Siedlce University of Natural Sciences and Humanities, 3 Maja 54, 08-110 Siedlce, Poland.

Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, 61-614 Poznań, Poland.

出版信息

Molecules. 2023 Jun 1;28(11):4482. doi: 10.3390/molecules28114482.

Abstract

Stilbene and its derivatives belong to the group of biologically active compounds. Some derivatives occur naturally in various plant species, while others are obtained by synthesis. Resveratrol is one of the best-known stilbene derivatives. Many stilbene derivatives exhibit antimicrobial, antifungal or anticancer properties. A thorough understanding of the properties of this group of biologically active compounds, and the development of their analytics from various matrices, will allow for a wider range of applications. This information is particularly important in the era of increasing incidence of various diseases hitherto unknown, including COVID-19, which is still present in our population. The purpose of this study was to summarize information on the qualitative and quantitative analysis of stilbene derivatives, their biological activity, potential applications as preservatives, antiseptics and disinfectants, and stability analysis in various matrices. Optimal conditions for the analysis of the stilbene derivatives in question were developed using the isotachophoresis technique.

摘要

二苯乙烯及其衍生物属于具有生物活性的化合物。一些衍生物天然存在于各种植物物种中,而另一些则通过合成获得。白藜芦醇是最著名的二苯乙烯衍生物之一。许多二苯乙烯衍生物具有抗菌、抗真菌或抗癌特性。深入了解这组具有生物活性的化合物的特性,并从各种基质中开发它们的分析方法,将允许更广泛的应用。在各种疾病发病率不断上升的时代,包括目前仍在我们人群中存在的 COVID-19,这些信息尤为重要。本研究的目的是总结二苯乙烯衍生物的定性和定量分析、生物活性、作为防腐剂、防腐剂和消毒剂的潜在应用以及各种基质中稳定性分析方面的信息。使用等速电泳技术开发了所讨论的二苯乙烯衍生物的分析最佳条件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c11/10254445/a526710a52c3/molecules-28-04482-g001.jpg

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