Porcu Stefania, Maloccu Stefania, Corona Angela, Hazra Moulika, David Tullia Carla, Chiriu Daniele, Carbonaro Carlo Maria, Tramontano Enzo, Ricci Pier Carlo
Department of Physics, University of Cagliari, 09042 Cagliari, Italy.
Department of Life and Environmental Sciences, University of Cagliari, 09124 Cagliari, Italy.
Polymers (Basel). 2023 May 31;15(11):2536. doi: 10.3390/polym15112536.
It is well known that viruses cannot replicate on their own but only inside the cells of target tissues in the organism, resulting in the destruction of the cells or, in some cases, their transformation into cancer cells. While viruses have relatively low resistance in the environment, their ability to survive longer is based on environmental conditions and the type of substrate on which they are deposited. Recently, the potential for safe and efficient viral inactivation by photocatalysis has garnered increasing attention. In this study, the Phenyl carbon nitride/TiO heterojunction system, a hybrid organic-inorganic photocatalyst, was utilized to investigate its effectiveness in degrading the flu virus (H1N1). The system was activated by a white-LED lamp, and the process was tested on MDCK cells infected with the flu virus. The results of the study demonstrate the hybrid photocatalyst's ability to cause the virus to degrade, highlighting its effectiveness for safe and efficient viral inactivation in the visible light range. Additionally, the study underscores the advantages of using this hybrid photocatalyst over traditional inorganic photocatalysts, which typically only work in the ultraviolet range.
众所周知，病毒无法自行复制，只能在生物体靶组织的细胞内进行复制，从而导致细胞被破坏，在某些情况下，还会使其转化为癌细胞。虽然病毒在环境中的抵抗力相对较低，但它们在更长时间内存活的能力取决于环境条件以及它们所附着的底物类型。最近，光催化实现安全高效病毒灭活的潜力受到了越来越多的关注。在本研究中，利用苯碳氮化物/二氧化钛异质结体系（一种有机-无机混合光催化剂）来研究其降解流感病毒（H1N1）的效果。该体系由白色发光二极管灯激活，并在感染流感病毒的犬肾上皮细胞（MDCK）上进行了测试。研究结果表明，这种混合光催化剂能够使病毒降解，突出了其在可见光范围内实现安全高效病毒灭活的有效性。此外，该研究强调了使用这种混合光催化剂相对于传统无机光催化剂的优势，传统无机光催化剂通常只在紫外光范围内起作用。
