Office of Cancer Survivorship, Division of Cancer Control and Population Sciences, National Cancer Institute, 9609 Medical Center Drive, MSC 9712, Room 4E440, Bethesda, MD, 20892-9762, USA.
Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA.
J Cancer Surviv. 2024 Oct;18(5):1443-1452. doi: 10.1007/s11764-023-01414-0. Epub 2023 Jun 10.
To describe the characteristics of National Institutes of Health (NIH) cancer survivorship grants funded over the past 5 years and identify gap areas for future efforts and initiatives.
Research project grants (RPG) funded during Fiscal Year (FY) 2017 to 2021 focused on cancer survivorship were identified using a text mining algorithm of words from the NIH Research, Condition, and Disease Categorization (RCDC) thesaurus with survivorship-relevant terms. The title, abstract, specific aims, and public health relevance section of each grant were reviewed for eligibility. Grants meeting the eligibility criteria were double coded to extract study characteristics (e.g., grant mechanism, study design, study population).
A total of 586 grants were funded by 14 NIH Institutes from FY2017 to FY2021, and the number of newly funded grants increased each FY, from 68 in 2017 to 105 in 2021. Approximately 60% of all grants included an intervention study, and interventions most often focused on psychosocial or supportive care (32.0%). The most common primary focus of the grants was late- and long-term effects of cancer treatment (46.6%), and least often financial hardship.
The results of this portfolio analysis indicate overall growth in the number and breadth of grants over the last five years, although notable gaps persist.
This review of current NIH grants suggests a need for expanded research to understand and address survivor needs to ensure that the over 18 million cancer survivors in the United States have optimal quality of life and health outcomes.
描述过去 5 年美国国立卫生研究院（NIH）癌症生存研究资助的特点，并确定未来努力和倡议的差距领域。
使用 NIH 研究、状况和疾病分类（RCDC）词库中的生存相关术语的文本挖掘算法，确定 2017 财年至 2021 财年资助的重点关注癌症生存的研究项目资助（RPG）。审查每份赠款的标题、摘要、具体目标和公共卫生相关性部分，以确定其是否符合资格。符合资格标准的赠款进行双编码，以提取研究特征（例如，赠款机制、研究设计、研究人群）。
从 2017 财年到 2021 财年，14 个 NIH 机构共资助了 586 项赠款，新资助的赠款数量每年都在增加，从 2017 年的 68 项增加到 2021 年的 105 项。约 60%的赠款包含干预研究，干预措施最常集中在心理社会或支持性护理方面（32.0%）。赠款的最常见主要重点是癌症治疗的晚期和长期影响（46.6%），而最不常见的是经济困难。
该投资组合分析的结果表明，过去五年中赠款的数量和范围总体上有所增加，但仍存在明显差距。
对当前 NIH 赠款的审查表明，需要扩大研究范围，以了解和解决幸存者的需求，确保美国超过 1800 万癌症幸存者拥有最佳的生活质量和健康结果。
