Suppr超能文献

多中心队列中胸痛患者心脏检查率的种族差异。

Race differences in cardiac testing rates for patients with chest pain in a multisite cohort.

作者信息

Popp Lucas M, Ashburn Nicklaus P, Snavely Anna C, Allen Brandon R, Christenson Robert H, Madsen Troy, Mumma Bryn E, Nowak Richard, Stopyra Jason P, Wilkerson R Gentry, Mahler Simon A

机构信息

Department of Emergency Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

Section on Cardiovascular Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

出版信息

Acad Emerg Med. 2023 Oct;30(10):1020-1028. doi: 10.1111/acem.14762. Epub 2023 Jun 19.

Abstract

BACKGROUND

Identifying and eliminating racial health care disparities is a public health priority. However, data evaluating race differences in emergency department (ED) chest pain care are limited.

METHODS

We conducted a secondary analysis of the High-Sensitivity Cardiac Troponin T to Optimize Chest Pain Risk Stratification (STOP-CP) cohort, which prospectively enrolled adults with symptoms suggestive of acute coronary syndrome without ST-elevation from eight EDs in the United States from 2017 to 2018. Race was self-reported by patients and abstracted from health records. Rates of 30-day noninvasive testing (NIT), cardiac catheterization, revascularization, and adjudicated cardiac death or myocardial infarction (MI) were determined. Logistic regression was used to evaluate the association between race and 30-day outcomes with and without adjustment for potential confounders.

RESULTS

Among 1454 participants, 42.3% (615/1454) were non-White. At 30 days NIT occurred in 31.4% (457/1454), cardiac catheterization in 13.5% (197/1454), revascularization in 6.0% (87/1454), and cardiac death or MI in 13.1% (190/1454). Among Whites versus non-Whites, NIT occurred in 33.8% (284/839) versus 28.1% (173/615; odds ratio [OR] 0.76, 95% confidence interval [CI] 0.61-0.96) and catheterization in 15.9% (133/839) versus 10.4% (64/615; OR 0.62, 95% CI 0.45-0.84). After covariates were adjusted for, non-White race remained associated with decreased 30-day NIT (adjusted OR [aOR] 0.71, 95% CI 0.56-0.90) and cardiac catheterization (aOR 0.62, 95% CI 0.43-0.88). Revascularization occurred in 6.9% (58/839) of Whites versus 4.7% (29/615) of non-Whites (OR 0.67, 95% CI 0.42-1.04). Cardiac death or MI at 30 days occurred in 14.2% of Whites (119/839) versus 11.5% (71/615) of non-Whites (OR 0.79 95% CI 0.57-1.08). After adjustment there was still no association between race and 30-day revascularization (aOR 0.74, 95% CI 0.45-1.20) or cardiac death or MI (aOR 0.74, 95% CI 0.50-1.09).

CONCLUSIONS

In this U.S. cohort, non-White patients were less likely to receive NIT and cardiac catheterization compared to Whites but had similar rates of revascularization and cardiac death or MI.

摘要

背景

识别并消除种族间医疗保健差异是一项公共卫生重点工作。然而,评估急诊科胸痛护理中种族差异的数据有限。

方法

我们对高敏心肌肌钙蛋白T优化胸痛风险分层(STOP-CP)队列进行了二次分析,该队列在2017年至2018年期间前瞻性纳入了来自美国8家急诊科的有急性冠状动脉综合征症状但无ST段抬高的成年人。种族由患者自行报告,并从健康记录中提取。确定了30天非侵入性检测(NIT)、心导管插入术、血运重建以及判定的心脏死亡或心肌梗死(MI)的发生率。采用逻辑回归分析评估种族与30天结局之间的关联,分析时调整和未调整潜在混杂因素。

结果

在1454名参与者中,42.3%(615/1454)为非白人。30天时,NIT发生率为31.4%(457/1454),心导管插入术发生率为13.5%(197/1454),血运重建发生率为6.0%(87/1454),心脏死亡或MI发生率为13.1%(190/1454)。白人组与非白人组相比,NIT发生率分别为33.8%(284/839)和28.1%(173/615);优势比(OR)为0.76,95%置信区间(CI)为0.61 - 0.96;心导管插入术发生率分别为15.9%(133/839)和10.4%(64/615);OR为0.62,95%CI为0.45 - 0.84。调整协变量后,非白人种族与30天NIT减少(调整后OR[aOR]为0.71,95%CI为0.56 - 0.90)以及心导管插入术减少(aOR为0.62,95%CI为0.43 - 0.88)仍然相关。白人组血运重建发生率为6.9%(58/839),非白人组为4.7%(29/615);OR为0.67,95%CI为0.42 - 1.04。30天时白人组心脏死亡或MI发生率为14.2%(119/839),非白人组为11.5%(71/615);OR为0.79,95%CI为0.57 - 1.08。调整后,种族与30天血运重建(aOR为0.74,95%CI为0.45 - 1.20)或心脏死亡或MI(aOR为0.74,95%CI为0.50 - 1.09)之间仍无关联。

结论

在这个美国队列中,与白人相比,非白人患者接受NIT和心导管插入术的可能性较小,但血运重建以及心脏死亡或MI的发生率相似。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验