老年住院患者过度用药的流行率及其预测因素：印度尼西亚的一项回顾性横断面研究。
Prevalence and Predictors of Excessive Polypharmacy in Geriatric Inpatients: A Retrospective Cross-Sectional Study in Indonesia.
机构信息
Universitas Airlangga, Surabaya, Indonesia.
Mahidol University, Bangkok, Thailand.
出版信息
J Prim Care Community Health. 2023 Jan-Dec;14:21501319231178595. doi: 10.1177/21501319231178595.
OBJECTIVES
To investigate the prevalence and predictors of excessive polypharmacy in geriatric inpatients in Indonesia.
METHODS
This retrospective cross-sectional study included 1533 inpatients over the age of 60 years at Universitas Airlangga Hospital, Indonesia. Effects of a patient's baseline characteristics on excessive polypharmacy were evaluated using logistic regression analysis.
RESULTS
Excessive polypharmacy was observed in 133 (8.67%) patients. Ulcer (OR 8.151,95% CI 2.234-29.747, = .001), cancer (OR 5.551, 95% CI 1.602-19.237, = .007), and renal diseases (OR 3.710, 95% CI 1.965-7.006, < .001) were the 3 strongest predictors of excessive polypharmacy. An association between hospital stay of more than 3 days and excessive polypharmacy was identified (OR 2.382, 95% CI 1.109-5.115, = .026).
DISCUSSION
One in 12 elderly Indonesians was found to practice excessive polypharmacy. Several chronic conditions and increased length of hospital stay were the factors associated with excessive polypharmacy.
目的
调查印度尼西亚老年住院患者中过度用药的流行情况及其预测因素。
方法
本回顾性横断面研究纳入了印度尼西亚 Airlangga 大学医院 1533 名年龄在 60 岁以上的住院患者。使用逻辑回归分析评估患者基线特征对过度用药的影响。
结果
133 名（8.67%）患者存在过度用药。溃疡（OR 8.151，95%CI 2.234-29.747， = .001）、癌症（OR 5.551，95%CI 1.602-19.237， = .007）和肾脏疾病（OR 3.710，95%CI 1.965-7.006， < .001）是过度用药的 3 个最强预测因素。住院时间超过 3 天与过度用药之间存在关联（OR 2.382，95%CI 1.109-5.115， = .026）。
讨论
12 名老年印度尼西亚人中就有 1 人存在过度用药。几种慢性疾病和住院时间延长是与过度用药相关的因素。
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