Hao Qiukui, Hu Xiaoyi, Xie Linlin, Chen Jing, Jiang Jiaojiao, Dong Birong, Yang Ming
The Center of Gerontology and Geriatrics, West China Hospital of Sichuan University, Chengdu, China.
The Center of Rehabilitation, West China Hospital of Sichuan University, Chengdu, China.
Australas J Ageing. 2018 Mar;37(1):62-67. doi: 10.1111/ajag.12492. Epub 2018 Jan 5.
To estimate the prevalence and factors associated with sarcopenia in a sample of older inpatients.
A cross-sectional study was conducted in three acute geriatric wards in 2012. Sarcopenia was defined according to the criteria of the Asian Working Group for Sarcopenia.
We included 407 patients aged 81.0 ± 8.0 years. The prevalence of sarcopenia was 31% in the whole study population. Multiple logistic regression showed that being a female (odds ratio (OR) 4.75, 95% confidence interval (CI) 2.45-9.20), smoking (OR 2.94, 95% CI 1.26-6.69), cognitive impairment (OR 2.08, 95% CI 1.10-3.95), polypharmacy (OR 2.36, 95% CI 1.28-4.34) and body mass index (OR 0.75, 95% CI 0.68-0.83) were independently associated with sarcopenia.
Sarcopenia was highly prevalent in older inpatients. In addition to factors previously reported to be associated with sarcopenia, we found that polypharmacy was associated with sarcopenia. As the direction of causality remains uncertain, these relationships deserve further study.
评估老年住院患者样本中肌肉减少症的患病率及其相关因素。
2012年在三个急性老年病房开展了一项横断面研究。肌肉减少症根据亚洲肌肉减少症工作组的标准进行定义。
我们纳入了407名年龄为81.0 ± 8.0岁的患者。整个研究人群中肌肉减少症的患病率为31%。多因素logistic回归显示，女性（比值比（OR）4.75，95%置信区间（CI）2.45 - 9.20）、吸烟（OR 2.94，95% CI 1.26 - 6.69）、认知障碍（OR 2.08，95% CI 1.10 - 3.95）、多重用药（OR 2.36，95% CI 1.28 - 4.34）和体重指数（OR 0.75，95% CI 0.68 - 0.83）与肌肉减少症独立相关。
肌肉减少症在老年住院患者中非常普遍。除了先前报道的与肌肉减少症相关的因素外，我们发现多重用药与肌肉减少症有关。由于因果关系的方向仍不确定，这些关系值得进一步研究。
