Department of Oral Medicine and Radiology D Y Patil University, School of Dentistry, Navi Mumbai, India.
D Y Patil University, School of Dentistry, Navi Mumbai, India.
Pol J Pathol. 2023;74(1):51-55. doi: 10.5114/pjp.2023.127012.
Lobular capillary hemangioma, a benign vascular tumor of the skin or mucous membranes characterized by rapid growth and a friable surface, is widely but inappropriately termed pyogenic granuloma (now considered a misnomer by some theories) due to lack of evidence for infectious etiopathogenesis. Some studies promote the theory of a hyperplastic, neovascular response to an angiogenic stimulus with imbalance of promoters and inhibitors. Here we present a series of 4 cases of patients who visited the Oral Medicine OPD with a complaint of similar painless malformations showing granulomatous and/or fibrous tissue proliferation andwhich, after thorough history taking, clinical examination and excisional biopsy, were revealed to be lobular capillary hemangioma under histopathologic diagnosis. The following discussion revolves around the fact that, even though such exophytic lesions may present with variable features, a proper, accurate and logical diagnostic entity may be used to help in better coordination among the oral physician, oral pathologist and oral surgeon in framing the desired treatment plan.
小叶状毛细血管瘤，一种皮肤或黏膜的良性血管肿瘤，其特征为快速生长和表面易碎，由于缺乏感染病因发病机制的证据，被广泛但不恰当地称为化脓性肉芽肿（现在一些理论认为这是一个错误的命名）。一些研究提出了一种增生性、新生血管反应的理论，认为这是一种血管生成刺激物的不平衡，促进了启动子和抑制剂的失衡。在这里，我们介绍了一系列 4 例患者，他们因类似的无痛性畸形就诊于口腔医学门诊，表现为肉芽肿和/或纤维组织增生，经过详细的病史询问、临床检查和切除活检，在组织病理学诊断下被发现为小叶状毛细血管瘤。以下讨论围绕着这样一个事实，即尽管这些外生性病变可能表现出不同的特征，但一个适当、准确和合理的诊断实体可以用来帮助口腔医生、口腔病理学家和口腔外科医生更好地协调，制定理想的治疗计划。
