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在国防部卫生服务医院实施入院和出院时的药物重整:一项多中心研究。

Implementation of medication reconciliation at admission and discharge in Ministry of Defense Health Services hospitals: a multicentre study.

机构信息

Continuous Quality Improvement and Patient Safety, Kingdom of Saudi Arabia General Department of Medical Services, Riyadh, Saudi Arabia

Pharmaceutical Care Department, Kingdom of Saudi Arabia General Department of Medical Services, Riyadh, Saudi Arabia.

出版信息

BMJ Open Qual. 2023 Jun;12(2). doi: 10.1136/bmjoq-2022-002121.

Abstract

There is potential for many medication errors to occur due to the complex medication use process. The medication reconciliation process can significantly lower the incidence of medication errors that may arise from an incomplete or inaccurate medication history as well as reductions in length of hospital stay, patients' readmissions and lower healthcare costs.The quality improvement collaborative project was conducted as a pilot study in two hospitals, then implemented on a broader scale in 18 hospitals in Saudi Arabia. The goal of the project was to reduce the percentage of patients with at least one outstanding unintentional discrepancy at admission by 50%, over 16-month period (July 2020-November 2021). Our interventions were based on the High 5's project medication reconciliation WHO, and Medications at Transitions and Clinical Handoffs toolkit for medication reconciliation by Agency for Healthcare Research and Quality. Improvement teams used the Institute of Healthcare Improvement's (IHI's) Model for improvement as a tool for testing and implementing changes. Collaboration and learning between hospitals were facilitated by conducting learning sessions using the IHI's Collaborative Model for Achieving Breakthrough Improvement. The improvement teams underwent three cycles.By the end of the project significant improvements were observed. The percentage of patients with at least one outstanding unintentional discrepancy at admission showed a 20% reduction (27% before, 7% after; p value <0.05) (Relative Risk (RR) 0.74) with a mean reduction in the number of discrepancies per patient by 0.74. The percentage of patients with at least one outstanding unintentional discrepancy at discharge showed 12% reduction (17% before, 5% after; p value <0.05) (RR 0.71) with a mean reduction in the number of discrepancies per patient by 0.34.Compliance to medication reconciliation documentation within 24 hours of admission and discharge showed significant improvement by an average of 17% and 24%, respectively. Additionally, the implementation of medication reconciliation had a negative correlation with the percentage of patients with at least one outstanding unintentional discrepancy at admission and discharge.

摘要

由于复杂的用药流程,可能会发生许多用药错误。用药核对流程可以显著降低因用药史不完整或不准确而导致的用药错误发生率,缩短住院时间、减少患者再入院率并降低医疗成本。该质量改进合作项目首先在两家医院进行试点研究,然后在沙特阿拉伯的 18 家医院进行更广泛的实施。该项目的目标是在 16 个月(2020 年 7 月至 2021 年 11 月)内,将至少有一项入院时未解决的非故意差异的患者比例降低 50%。我们的干预措施基于世界卫生组织(WHO)的 High 5's 项目用药核对、医疗机构用药过渡和临床交接工具包,以及美国医疗保健研究与质量署的用药核对。改进团队使用美国医疗保健改进研究所(IHI)的改进模型作为测试和实施变更的工具。通过使用 IHI 的突破性改进协作模型开展学习会议,促进了医院之间的协作和学习。改进团队经历了三个循环。在项目结束时,观察到了显著的改进。至少有一项入院时未解决的非故意差异的患者比例降低了 20%(之前为 27%,之后为 7%;p 值<0.05)(相对风险(RR)为 0.74),每位患者的差异数量平均减少了 0.74。至少有一项出院时未解决的非故意差异的患者比例降低了 12%(之前为 17%,之后为 5%;p 值<0.05)(RR 为 0.71),每位患者的差异数量平均减少了 0.34。入院和出院后 24 小时内完成用药核对文档的比例分别提高了 17%和 24%,这一比例有显著改善。此外,用药核对的实施与至少有一项入院和出院时未解决的非故意差异的患者比例呈负相关。

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