在缺铁的生理介质中定义 22 种利福霉素对鲍曼不动杆菌、大肠杆菌和肺炎克雷伯菌临床分离株的最小抑菌浓度。
Defining the minimum inhibitory concentration of 22 rifamycins in iron limited, physiologic medium against Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae clinical isolates.
机构信息
Department of Molecular Microbiology and Immunology, Keck School of Medicine at USC, Los Angeles, California, United States of America.
Department of Life Science, University of Modena and Reggio Emilia, Modena, Italy.
出版信息
PLoS One. 2023 Jun 13;18(6):e0287102. doi: 10.1371/journal.pone.0287102. eCollection 2023.
Recently, we reported rifabutin hyper-activity against Acinetobacter baumannii. We sought to characterize if any additional rifamycins (n = 22) would also display hyper-activity when tested in iron-limited media against A. baumannii, K. pneumoniae, and E. coli. MICs were determined against representative clinical isolates using the iron-limited media RPMI-1640. Only rifabutin was hyperactive against A. baumannii.
最近，我们报道了利福布汀对鲍曼不动杆菌的超活性。我们试图研究，如果在缺铁培养基中对鲍曼不动杆菌、肺炎克雷伯菌和大肠杆菌进行测试时，是否还有其他利福霉素（n=22）也会显示出超活性。使用缺铁培养基 RPMI-1640 对代表性临床分离株进行 MIC 测定。只有利福布汀对鲍曼不动杆菌具有超活性。
Zotero 插件