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潜在的卤代工业致癌和致突变化学品。II. 卤代饱和烃。

Potential halogenated industrial carcinogenic and mutagenic chemicals. II. Halogenated saturated hydrocarbons.

作者信息

Fishbein L

出版信息

Sci Total Environ. 1979 Mar;11(2):163-95. doi: 10.1016/0048-9697(79)90026-3.

Abstract

The halogenated saturated hydrocarbons analogously to the previously considered halogenated unsaturated hydrocarbons (Part I) possess considerable utility in a broad spectrum of applications including; solvents, dry-cleaning fluids, refrigerants, fumigants, degreasing agents, propellants and intermediates in the production of other chemicals, textiles and plastics. Methyl chloride, methylene chloride, chloroform, carbon tetrachloride, methyl chloroform, 1,1,2-trichloroethane, hexachloroethane, ethyl chloride and fluorocarbons were reviewed principally in terms of their synthesis (or occurrence), areas of application, stability, distribution, reactivity, levels of exposure, populations at risk, carcinogenicity, mutagenicity and metabolism.

摘要

与之前讨论过的卤代不饱和烃(第一部分)类似,卤代饱和烃在广泛的应用领域中具有相当大的用途,包括:溶剂、干洗液、制冷剂、熏蒸剂、脱脂剂、推进剂以及其他化学品、纺织品和塑料生产中的中间体。主要从合成(或来源)、应用领域、稳定性、分布、反应性、接触水平、风险人群、致癌性、致突变性和代谢等方面对氯甲烷、二氯甲烷、氯仿、四氯化碳、甲基氯仿、1,1,2-三氯乙烷、六氯乙烷、氯乙烷和碳氟化合物进行了综述。

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