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潜在的卤代工业致癌和致突变化学品。IV. 卤代芳基衍生物。

Potential halogenated industrial carcinogenic and mutagenic chemicals. IV. Halogenated aryl derivatives.

作者信息

Fishbein L

出版信息

Sci Total Environ. 1979 Apr;11(3):259-78. doi: 10.1016/0048-9697(79)90077-9.

Abstract

A variety of halogenated aryl derivatives possess significant activity as solvents for pesticides, heat transfer agents, pesticide intermediates, additives for rubber products, intermediates in organic synthesis and as insect repellants and deodorants. Ortho- and para-dichlorobenzenes; 1,2,4-trichloro- and hexachlorobenzene, as well as bromobenzenes and benzylchloride were reviewed principally in terms of their synthesis, areas of utility, stability, distribution, reactivity, levels of exposure, populations at risk, metabolism, carcinogenicity and mutagenicity.

摘要

多种卤代芳基衍生物作为农药溶剂、热传递剂、农药中间体、橡胶制品添加剂、有机合成中间体以及驱虫剂和除臭剂具有显著活性。邻二氯苯和对二氯苯;1,2,4-三氯苯和六氯苯,以及溴苯和苄基氯主要从其合成、用途领域、稳定性、分布、反应性、暴露水平、风险人群、代谢、致癌性和致突变性等方面进行了综述。

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