von Stempel Conrad, Shahzad Rohaan, Walkden Miles, Castiglione Fabio, Muneer Asif, Ralph David, Kirkham Alex
Department of Radiology, University College London Hospitals, London, UK.
Division of Surgery and Interventional Science, University College London, London, UK.
Int J Impot Res. 2024 Feb;36(1):55-61. doi: 10.1038/s41443-023-00719-z. Epub 2023 Jun 13.
Non-ischemic priapism (NiP) is painless partial tumescence caused by genital trauma and the formation of intracorporal arterio-venous fistula. This is a retrospective study of 25 men with NiP and reports the long-term erectile function and colour doppler ultrasound (CDUS) findings after treatment for NiP. Unstimulated CDUS was performed at diagnosis, 1 week and at last follow-up after treatment. CDUS traces were analysed: peak systolic velocity (PSV), end diastolic velocity (EDV), resistive index (RI) and mean velocity (MV) were calculated. Erectile function was assessed using the IIEF-EF questionnaire. At the last follow-up (median 24 months), 16 men had normal erectile function (64%): median IIEF-EF score 29 (IQR 28.5-30; σ 2.78) and nine had erectile dysfunction (36%): median IIEF-EF score 17 (IQR 14-22; σ 33.6). MV and EDV were statistically higher in those patients with erectile dysfunction at last follow-up compared to patients with normal erectile function: median MV 5.3 cm/s (IQR 2.4-10.5 cm/s; σ 34) vs 2.95 cm/s (IQR 1.03-3.95; σ 3.4) p < 0.002 and median EDV 4.0 cm/s (IQR 1.5-8.0; σ 14.7) vs 0 cm/s (IQR 0-1.75; σ 2.21) p < 0.004. Erectile dysfunction was observed in 36% of men treated for NiP and was associated with abnormal low resistance resting CDUS waveforms. Further investigation for persistent arteriovenous fistulation should be considered in these patients.
非缺血性阴茎异常勃起(NiP)是由生殖器创伤和体内动静脉瘘形成引起的无痛性部分肿胀。这是一项对25例NiP男性患者的回顾性研究,报告了NiP治疗后的长期勃起功能和彩色多普勒超声(CDUS)检查结果。在诊断时、治疗后1周及最后一次随访时进行非刺激状态下的CDUS检查。分析CDUS轨迹:计算收缩期峰值流速(PSV)、舒张末期流速(EDV)、阻力指数(RI)和平均流速(MV)。使用国际勃起功能指数-勃起功能(IIEF-EF)问卷评估勃起功能。在最后一次随访时(中位时间24个月),16名男性勃起功能正常(64%):IIEF-EF评分中位数为29(四分位间距28.5 - 30;标准差2.78),9名男性存在勃起功能障碍(36%):IIEF-EF评分中位数为17(四分位间距14 - 22;标准差33.6)。与勃起功能正常的患者相比,最后一次随访时存在勃起功能障碍的患者MV和EDV在统计学上更高:MV中位数为5.3厘米/秒(四分位间距2.4 - 10.5厘米/秒;标准差34),而正常勃起功能患者为2.95厘米/秒(四分位间距1.03 - 3.95;标准差3.4),p < 0.002;EDV中位数为4.0厘米/秒(四分位间距1.5 - 8.0;标准差14.7),而正常勃起功能患者为0厘米/秒(四分位间距0 - 1.75;标准差2.21),p < 0.004。在接受NiP治疗的男性中,36%出现勃起功能障碍,且与静息状态下CDUS波形阻力异常降低有关。对于这些患者,应考虑进一步检查是否存在持续性动静脉瘘。