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中医治疗慢性胃炎的进展:从慢性非萎缩性胃炎到胃癌前病变

Progress in traditional Chinese medicine against chronic gastritis: From chronic non-atrophic gastritis to gastric precancerous lesions.

作者信息

Yang Liangjun, Liu Xinying, Zhu Jiajie, Zhang Xi, Li Ya, Chen Jiabing, Liu Haiyan

机构信息

Tongde Hospital of Zhejiang Province, Hangzhou 310012, China.

Guangzhou University of Chinese Medicine, Guangzhou 510405, China.

出版信息

Heliyon. 2023 May 27;9(6):e16764. doi: 10.1016/j.heliyon.2023.e16764. eCollection 2023 Jun.

Abstract

Chronic gastritis (CG) is a persistent inflammation of the gastric mucosa that can cause uncomfortable symptoms in patients. Traditional Chinese medicine (TCM) has been widely used to treat CG due to its precise efficacy, minimal side effects, and holistic approach. Clinical studies have confirmed the effectiveness of TCM in treating CG, although the mechanisms underlying this treatment have not yet been fully elucidated. In this review, we summarized the clinical research and mechanisms of TCM used to treat CG. Studies have shown that TCM mechanisms for CG treatment include eradication, anti-inflammatory effects, immune modulation, regulation of gastric mucosal cell proliferation, apoptosis, and autophagy levels.

摘要

慢性胃炎(CG)是胃黏膜的持续性炎症,可导致患者出现不适症状。由于其疗效确切、副作用小且采用整体治疗方法,传统中医(TCM)已被广泛用于治疗慢性胃炎。临床研究已证实中医治疗慢性胃炎的有效性,尽管这种治疗的潜在机制尚未完全阐明。在本综述中,我们总结了中医治疗慢性胃炎的临床研究及其机制。研究表明,中医治疗慢性胃炎的机制包括根除、抗炎作用、免疫调节、调节胃黏膜细胞增殖、凋亡及自噬水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d726/10258419/6f46e24eac76/gr1.jpg

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