Waszczuk-Gajda Anna, Szafraniec-Buryło Sylwia, Kraj Leszek, Skwierawska Kamila, Aleksandrowicz Kinga, Basak Grzegorz Władysław, Brzozowska Melania, Wierzba Waldemar, Jędrzejczak Wiesław Wiktor, Śliwczyński Andrzej
Department of Haematology, Oncology and Internal Diseases, Warsaw Medical University, Warsaw, Poland.
Department of Pharmacoeconomics, Institute of Mother and Child, Warsaw, Poland.
Arch Med Sci. 2020 Feb 6;19(3):645-650. doi: 10.5114/aoms.2020.92908. eCollection 2023.
Multiple myeloma is the third most common blood cancer in Europe and accounts for approx. 10-15% of these cancers. The objective of this study was to determine the incidence, prevalence, mortality and survival in multiple myeloma (ICD code: C90.0) patients in Poland in the years 2008-2017.
The analysis used the data on healthcare services provided to patients with multiple myeloma defined with the ICD-10 (International Statistical Classification of Diseases and Related Health Problems) code C90.0 and reported by healthcare entities to the National Health Fund (NFZ).
In 2009, the C90.0 incidence per 100,000 inhabitants was 6.4, while in 2017 it was 8.3. The prevalence in the same period increased by 76%, from 13.6/100,000 to 23.9/100,000. The mortality to prevalence ratio gradually decreased from 78% in 2008 to 22.8% in 2017. The 1-year, 3-year and 5-year survival rates in patients with this diagnosis made in the years 2009 and 2013 were 70.5%, 51.5% and 40.2% versus 78.4%, 60.3% and 48.3%, respectively.
The incidence and prevalence of multiple myeloma and survival rates in Poland were continuously increasing in the studied period. These trends may result from the aging of Polish society, better recognisability of multiple myeloma and/or improved access to increasingly more effective therapies in Poland. The impact of these factors on the epidemiology of multiple myeloma requires further studies.
多发性骨髓瘤是欧洲第三大常见血液癌症,约占此类癌症的10 - 15%。本研究的目的是确定2008 - 2017年波兰多发性骨髓瘤(ICD编码:C90.0)患者的发病率、患病率、死亡率和生存率。
分析使用了医疗保健实体向国家卫生基金(NFZ)报告的、由ICD - 10(国际疾病和相关健康问题统计分类)编码C90.0定义的多发性骨髓瘤患者的医疗服务数据。
2009年,每10万居民中C90.0的发病率为6.4,而2017年为8.3。同期患病率增加了76%,从13.6/10万增至23.9/10万。死亡率与患病率之比从2008年的78%逐渐降至2017年的22.8%。2009年和2013年确诊的此类患者的1年、3年和5年生存率分别为70.5%、51.5%和40.2%,而分别为78.4%、60.3%和48.3%。
在研究期间,波兰多发性骨髓瘤的发病率、患病率和生存率持续上升。这些趋势可能是由于波兰社会老龄化、多发性骨髓瘤的可识别性提高和/或波兰获得越来越有效治疗的机会增加。这些因素对多发性骨髓瘤流行病学的影响需要进一步研究。