Alustiza Jose M, Castiella Agustin, Zapata Eva, Urreta Iratxe, Salvador Emma, Emparanza Jose I
Radiology Service, Osatek Donostia, Donostia, Spain.
Gastroenterology Service, Donostia University Hospital, Donostia, Spain.
Arch Med Sci. 2021 Feb 3;19(3):784-791. doi: 10.5114/aoms/119118. eCollection 2023.
Determination of liver iron concentration by magnetic resonance imaging (MRI) is becoming the new technique of choice for the diagnosis of iron overload in hereditary haemochromatosis and other liver iron surcharge diseases. Determination of hepatic iron concentration obtained by liver biopsy has been the gold standard for years. The development of MRI techniques, via signal intensity ratio methods or relaxometry, has provided a non-invasive and more accurate approach to the diagnosis of liver iron overload. This article reviews the available MRI methods for the determination of liver iron concentration and also evaluates the technique for the diagnosis and quantification of iron overload in different clinical practice scenarios.
通过磁共振成像（MRI）测定肝脏铁浓度正成为诊断遗传性血色素沉着症及其他肝脏铁过载疾病中铁过载的新技术选择。多年来，通过肝活检测定肝脏铁浓度一直是金标准。MRI技术通过信号强度比方法或弛豫测量法的发展，为肝脏铁过载的诊断提供了一种非侵入性且更准确的方法。本文回顾了现有的用于测定肝脏铁浓度的MRI方法，并评估了该技术在不同临床实践场景中铁过载的诊断和定量。
