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接受侧路腰椎椎间融合术患者住院时间延长的术前预测因素。

Preoperative predictors of prolonged hospitalization in patients undergoing lateral lumbar interbody fusion.

机构信息

Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St. Suite #300, Chicago, IL, 60612, USA.

出版信息

Acta Neurochir (Wien). 2023 Sep;165(9):2615-2624. doi: 10.1007/s00701-023-05648-w. Epub 2023 Jun 15.

Abstract

PURPOSE

We aim to examine the preoperative factors associated with increased postoperative length of stay in patients undergoing LLIF in the hospital setting.

METHODS

Patient demographics, perioperative characteristics, and patient-reported outcome measures (PROMs) were collected from a single-surgeon database. Patients undergoing LLIF in the hospital setting were separated into postoperative LOS <48 h (H) and LOS ≥ 48H. Univariate analysis for preoperative characteristics was utilized to determine covariates for multivariable logistic regression. Multivariable logistic regression was then utilized to determine significant predictors of extended postoperative length of stay. Secondary univariate analysis of inpatient complications, operative, and postoperative characteristics were calculated to determine postoperative factors associated with prolonged hospitalization.

RESULTS

Two-hundred and forty patients were identified with 115 patients' LOS ≥ 48H. Univariate analysis identified age/Charlson Comorbidity Index (CCI) score/gender/insurance type/number of contiguous fused levels/preoperative PROMs of Visual Analog Scale (VAS) back/VAS leg/Patient-Reported Outcomes Measurement Information System (PROMIS-PF)/Oswestry Disability Index (ODI)/degenerative spondylolisthesis diagnoses/foraminal stenosis/central stenosis for multivariable logistic regression. Multivariable logistic regression calculated significant positive predictors of LOS ≥ 48H to be age/3-level fusion/preoperative ODI scores. Negative predictors of LOS ≥ 48H were the diagnosis of foraminal stenosis/preoperative PROMIS-PF/male gender. The secondary analysis determined that patients with longer operative time/estimated blood loss/transfusion/postoperative day 0 and 1 pain and narcotic consumption/complications of altered mental status/postoperative anemia/fever/ileus/urinary retention were associated with prolonged hospitalization.

CONCLUSION

Older patients undergoing LLIF with greater preoperative disability and 3-level fusion were more likely to require prolonged hospitalization. Male patients with higher preoperative physical function and who were diagnosed with foraminal stenosis were less likely to require prolonged hospitalization.

摘要

目的

我们旨在研究接受腰椎经椎间孔椎体间融合术(LLIF)的患者中与术后住院时间延长相关的术前因素。

方法

从一位外科医生的数据库中收集了患者的人口统计学、围手术期特征和患者报告的结果测量指标(PROMs)。将在医院环境中接受 LLIF 的患者分为术后住院时间<48 小时(H)和住院时间≥48 小时的患者。利用单变量分析确定多变量逻辑回归的协变量。然后利用多变量逻辑回归确定延长术后住院时间的显著预测因素。对住院并发症、手术和术后特征进行二次单变量分析,以确定与住院时间延长相关的术后因素。

结果

确定了 240 名患者,其中 115 名患者的 LOS≥48H。单变量分析确定了年龄/Charlson 合并症指数(CCI)评分/性别/保险类型/连续融合水平数量/术前视觉模拟量表(VAS)背部/VAS 腿部/患者报告的结果测量信息系统(PROMIS-PF)/Oswestry 残疾指数(ODI)/退行性脊椎滑脱诊断/椎间孔狭窄/中央狭窄,用于多变量逻辑回归。多变量逻辑回归计算出 LOS≥48H 的显著正预测因素为年龄/3 级融合/术前 ODI 评分。LOS≥48H 的负预测因素为椎间孔狭窄/术前 PROMIS-PF/男性性别。二次分析确定,手术时间较长/估计失血量/输血/术后第 0 天和第 1 天疼痛和阿片类药物消耗/精神状态改变/术后贫血/发热/肠梗阻/尿潴留的并发症与住院时间延长相关。

结论

接受 LLIF 手术的年龄较大、术前残疾程度较高且融合 3 级的患者更有可能需要延长住院时间。术前身体功能较高且被诊断为椎间孔狭窄的男性患者不太可能需要延长住院时间。

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