Department of Nephrology, Provincial Clinical College, Fujian Medical University, Fujian Provincial Hospital, 350001, Fuzhou, China.
BMC Nephrol. 2023 Jun 16;24(1):177. doi: 10.1186/s12882-023-03230-1.
Peritoneal catheter related infection is one of the main complications and the major cause of technical failure of peritoneal dialysis (PD) treatment. However, PD catheter tunnel infection can be difficult to diagnosis and resolve. We presented a rare case in which a granuloma formation after repeated episodes of peritoneal dialysis catheter-related infection.
A 53-year-old female patient with kidney failure due to chronic glomerulonephritis treated with peritoneal dialysis for 7 years. The patient had repeated exit-site and tunnel inflammation, and repeated suboptimal courses of antibiotics. She switched to hemodialysis after 6 years in a local hospital without the peritoneal dialysis catheter being removed. The patient complained of an abdominal wall mass that lasted for several months. She was admitted to the Department of surgery to undergo mass resection. The resected tissue of the abdominal wall mass was sent for pathological examination. The result showed foreign body granuloma with necrosis and abscess formation. After the surgery, the infection did not recur.
The following key points can be learned from this case: 1. It is important to strengthen patient follow-up. 2.The PD catheter should be removed as early as possible in patients who do not need long-term PD, especially in patients with a history of exit-site and tunnel infections. 3. For patients presenting abnormal subcutaneous mass, attention should be paid to the possibility of the granuloma formation of infected Dacron cuffs of the PD catheter. If catheter infection occurs repeatedly, catheter removal and debridement should be considered.
腹膜透析管相关感染是腹膜透析(PD)治疗的主要并发症和技术失败的主要原因之一。然而,PD 导管隧道感染可能难以诊断和解决。我们报告了一例罕见的腹膜透析管相关感染后反复发生肉芽肿形成的病例。
一名 53 岁女性患者,因慢性肾小球肾炎导致肾功能衰竭,接受 PD 治疗 7 年。该患者出现出口部位和隧道炎症反复发作,且反复使用抗生素治疗效果欠佳。在当地医院接受 6 年治疗后,她转为血液透析,未取出 PD 导管。患者诉腹壁肿块持续数月。她到外科就诊,行肿块切除术。切除的腹壁肿块组织送病理检查。结果显示为异物肉芽肿伴坏死和脓肿形成。术后感染未再复发。
从该病例中可以得到以下要点:1. 加强患者随访非常重要。2.对于不需要长期 PD 的患者,应尽早取出 PD 导管,尤其是有出口部位和隧道感染史的患者。3.对于出现异常皮下肿块的患者,应注意 PD 导管感染的膨体聚四氟乙烯套圈肉芽肿形成的可能性。如果反复发生导管感染,应考虑取出导管并清创。