Aihemaiti Patiguli, Jia Ru, Aiyiti Wurikaixi, Jiang Houfeng, Kasimu Ayiguli
School of Mechanical Engineering, Xinjiang University, Urumqi 830000, PR China.
Int J Bioprint. 2023 Apr 19;9(4):734. doi: 10.18063/ijb.734. eCollection 2023.
A continuous polyglycolic acid (PGA) fiber-reinforced polylactic acid (PLA) degradable composite was proposed for application in biodegradable load-bearing bone implant. The fused deposition modeling (FDM) process was used to fabricate composite specimens. The influences of the printing process parameters, such as layer thickness, printing spacing, printing speed, and filament feeding speed on the mechanical properties of the PGA fiber-reinforced PLA composites, were studied. The thermal properties of the PGA fiber and PLA matrix were investigated by using differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). The internal defects of the as-fabricated specimens were characterized by the micro-X- ray 3D imaging system. During the tensile experiment, a full-field strain measurement system was used to detect the strain map and analysis the fracture mode of the specimens. A digital microscope and field emission electron scanning microscopy were used to observe the interface bonding between fiber and matrix and fracture morphologies of the specimens. The experimental results showed that the tensile strength of specimens was related to their fiber content and porosity. The printing layer thickness and printing spacing had significant impacts on the fiber content. The printing speed did not affect the fiber content but had a slight effect on the tensile strength. Reducing the printing spacing and layer thickness could increase the fiber content. The tensile strength (along the fiber direction) of the specimen with 77.8% fiber content and 1.82% porosity was the highest, reaching 209.32 ± 8.37 MPa, which is higher than the tensile strength of the cortical bone and polyether ether ketone (PEEK), indicating that the continuous PGA fiber-reinforced PLA composite has great potential in the manufacture of biodegradable load-bearing bone implants.
提出了一种连续聚乙醇酸（PGA）纤维增强聚乳酸（PLA）可降解复合材料，用于可生物降解承重骨植入物。采用熔融沉积成型（FDM）工艺制备复合材料试样。研究了层厚、打印间距、打印速度和送丝速度等打印工艺参数对PGA纤维增强PLA复合材料力学性能的影响。采用差示扫描量热法（DSC）和热重分析（TGA）研究了PGA纤维和PLA基体的热性能。利用微X射线3D成像系统对制备试样的内部缺陷进行表征。在拉伸试验中，使用全场应变测量系统检测应变图并分析试样的断裂模式。使用数码显微镜和场发射电子扫描显微镜观察纤维与基体之间的界面结合以及试样的断裂形态。实验结果表明，试样的拉伸强度与其纤维含量和孔隙率有关。打印层厚和打印间距对纤维含量有显著影响。打印速度不影响纤维含量，但对拉伸强度有轻微影响。减小打印间距和层厚可增加纤维含量。纤维含量为77.8%、孔隙率为1.82%的试样的拉伸强度（沿纤维方向）最高，达到209.32±8.37MPa，高于皮质骨和聚醚醚酮（PEEK）的拉伸强度，表明连续PGA纤维增强PLA复合材料在可生物降解承重骨植入物制造方面具有巨大潜力。
