Almohannadi Fatima S, Mesk Rami A, Braizat Omar M, Ahmed Mohamed B, Alsherawi Abeer
Department of Plastic and Reconstructive Surgery, Hamad Medical Corporation, Doha, QAT.
College of Medicine, QU Health, Qatar University, Doha, QAT.
Cureus. 2025 Jun 14;17(6):e86011. doi: 10.7759/cureus.86011. eCollection 2025 Jun.
Plexiform epithelioid schwannoma (PES) is a rare, benign nerve sheath tumor that can resemble malignant tumors, making diagnosis challenging. We present the case of a 46-year-old Filipino man with a slow-growing mass on his chin. After surgical excision, histopathology confirmed it as PES. Immunohistochemistry supported the diagnosis, showing strong S-100 and SOX10 positivity. The patient recovered well, with no signs of local recurrence. This case highlights the importance of thorough pathological evaluation when diagnosing rare tumors like PES.
丛状上皮样神经鞘瘤(PES)是一种罕见的良性神经鞘瘤,可类似恶性肿瘤,这使得诊断具有挑战性。我们报告一例46岁菲律宾男性患者,其下巴处有一生长缓慢的肿块。手术切除后,组织病理学证实为PES。免疫组织化学支持该诊断,显示S-100和SOX10强阳性。患者恢复良好,无局部复发迹象。该病例强调了在诊断像PES这样的罕见肿瘤时进行全面病理评估的重要性。