Chi Xiansu, Fan Xueming, Fu Guojing, Liu Yue, Zhang Yunling, Shen Wei
Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Front Pharmacol. 2023 May 30;14:1184830. doi: 10.3389/fphar.2023.1184830. eCollection 2023.
Post-stroke cognitive impairment (PSCI) is a major complication of stroke that affects more than one-third of stroke survivors, threatening their quality of life and increasing the risk of disability and death. Although various studies have described the etiology, epidemiology, and risk factors of PSCI, there are a limited number of comprehensive and accurate reports on research trends and hotspots in this field. Therefore, this review aimed to evaluate research trends, hotspots, and frontiers in PSCI using bibliometric analysis. We screened the literature spanning 20 years in the Web of Science Core Collection: Science Citation Index Expanded (SCI-Expanded) database from 1 January 2003 to 31 December 2022. We included all eligible literature reports based on our comprehensive search strategy, inclusion criteria, and exclusion criteria. The analysis of annual publications, countries/regions, institutions, journals, co-cited references, and keywords was conducted using CiteSpace and VOSviewer, and the hotspots and major findings of PSCI were summarized. A total of 1,024 publications were included in this review. We found that the number of publications on PSCI increased annually. These publications were published in 75 countries or regions by over 400 institutions. Although Chinese institutions had the highest number of publications, their international influence was limited. The United States showed a strong influence in the field. The journal "Stroke" published the most publications (57) with a high impact factor and was considered the most co-cited journal. The most frequently cited references focused on the prevalence, incidence, neuropsychological assessment scales, criteria, and guidelines of PSCI. The strongest citation burst keywords for PSCI were "neurotrophic factor" and "synaptic plasticity", which were regarded as research focuses and research hotspots, respectively. This review provided a comprehensive summary of the literature of PSCI, identified the authoritative and frequently cited literature and journals, clarified the trends in PSCI research, and highlighted the hotspots in this field. Currently, studies on the mechanisms and treatment of PSCI are limited, and we hope that this review has effectively highlighted the research trajectory of PSCI and will lay the foundation for more innovative research in the future.
中风后认知障碍（PSCI）是中风的一种主要并发症，影响超过三分之一的中风幸存者，威胁他们的生活质量，并增加残疾和死亡风险。尽管各种研究描述了PSCI的病因、流行病学和风险因素，但关于该领域研究趋势和热点的全面准确报告数量有限。因此，本综述旨在通过文献计量分析评估PSCI的研究趋势、热点和前沿。我们在科学网核心合集：科学引文索引扩展版（SCI-Expanded）数据库中筛选了20年的文献，时间跨度为2003年1月1日至2022年12月31日。我们根据全面的检索策略、纳入标准和排除标准纳入了所有符合条件的文献报告。使用CiteSpace和VOSviewer对年度出版物、国家/地区、机构、期刊、共被引参考文献和关键词进行分析，并总结PSCI的热点和主要发现。本综述共纳入1024篇出版物。我们发现，关于PSCI的出版物数量逐年增加。这些出版物由400多个机构在75个国家或地区发表。尽管中国机构的出版物数量最多，但其国际影响力有限。美国在该领域显示出强大的影响力。《中风》杂志发表的出版物最多（57篇），影响因子高，被认为是被引用最多的期刊。最常被引用的参考文献集中在PSCI的患病率、发病率、神经心理学评估量表、标准和指南上。PSCI最强的引文爆发关键词是“神经营养因子”和“突触可塑性”，它们分别被视为研究重点和研究热点。本综述对PSCI的文献进行了全面总结，确定了权威且常被引用的文献和期刊，阐明了PSCI的研究趋势，并突出了该领域的热点。目前，关于PSCI机制和治疗的研究有限，我们希望本综述有效地突出了PSCI的研究轨迹，并为未来更多的创新性研究奠定基础。
