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去大脑后条件性抑制性回避反应的存活情况。

Survival of a conditioned inhibitory avoidance response after decerebration.

作者信息

Tomaz C, Huston J P

出版信息

Exp Neurol. 1986 Jul;93(1):188-94. doi: 10.1016/0014-4886(86)90158-5.

DOI:10.1016/0014-4886(86)90158-5
PMID:3732458
Abstract

There is evidence that inhibitory avoidance learning is still possible after removal of the telencephalic forebrain. However, it is not known whether subtelencephalic storage of such a conditioned response takes place when the brain is intact. To investigate this possibility, rats received one training trial in the "up-hill avoidance" task, and 8 h later the entire forebrain except the hypothalamus was bilaterally ablated. When tested 24 h later, the decerebrate rats still exhibited the learned response, demonstrating a transfer of the conditioned response from the intact to the postlesion state. This result indicates that memory-storage for this avoidance task takes place, at least in part, subtelencephalically.

摘要

有证据表明,在切除端脑前脑后,抑制性回避学习仍然是可能的。然而,当大脑完整时,这种条件反应是否在端脑下储存尚不清楚。为了研究这种可能性,大鼠在“上坡回避”任务中接受一次训练试验,8小时后双侧切除除下丘脑以外的整个前脑。24小时后进行测试时,去脑大鼠仍表现出习得的反应,表明条件反应从完整状态转移到损伤后状态。这一结果表明,这种回避任务的记忆储存至少部分发生在端脑下。

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