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曲线变平:排队论的启示。

Flattening the curve: Insights from queueing theory.

机构信息

Cornell University Systems Engineering, Ithaca, NY, United States of America.

Cornell University Operations Research and Information Engineering, Ithaca, NY, United States of America.

出版信息

PLoS One. 2023 Jun 16;18(6):e0286501. doi: 10.1371/journal.pone.0286501. eCollection 2023.

Abstract

The worldwide outbreak of the coronavirus was first identified in 2019 in Wuhan, China. Since then, the disease has spread worldwide. As it is currently spreading in the United States, policy makers, public health officials and citizens are racing to understand the impact of this virus on the United States healthcare system. They fear a rapid influx of patients overwhelming the healthcare system and leading to unnecessary fatalities. Most countries and states in America have introduced mitigation strategies, such as using social distancing to decrease the rate of newly infected people. This is what is usually meant by flattening the curve. In this paper, we use queueing theoretic methods to analyze the time evolution of the number of people hospitalized due to the coronavirus. Given that the rate of new infections varies over time as the pandemic evolves, we model the number of coronavirus patients as a dynamical system based on the theory of infinite server queues with time inhomogeneous Poisson arrival rates. With this model we are able to quantify how flattening the curve affects the peak demand for hospital resources. This allows us to characterize how aggressive societal policy needs to be to avoid overwhelming the capacity of healthcare system. We also demonstrate how curve flattening impacts the elapsed lag between the times of the peak rate of hospitalizations and the peak demand for the hospital resources. Finally, we present empirical evidence from Italy and the United States that supports the insights from our model analysis.

摘要

全球范围内的冠状病毒疫情首次于 2019 年在中国武汉被发现。自那时以来,该疾病已在全球范围内传播。由于目前该病毒正在美国传播,政策制定者、公共卫生官员和公民正在竞相了解该病毒对美国医疗保健系统的影响。他们担心大量的患者涌入会使医疗系统不堪重负,导致不必要的死亡。大多数美国的国家和州都采取了缓解策略,例如使用社交距离来降低新感染人数的增长率。这就是通常所说的“曲线变平”。在本文中,我们使用排队论方法分析了因冠状病毒而住院的人数的时间演变。由于随着大流行的发展,新感染率会随时间变化,因此我们根据具有时间非齐次泊松到达率的无限服务器队列理论,将冠状病毒患者的数量建模为一个动态系统。通过这个模型,我们可以量化曲线变平如何影响医院资源的峰值需求。这使我们能够描述社会政策需要采取多大的力度来避免使医疗系统的容量不堪重负。我们还展示了曲线变平如何影响住院高峰期和医院资源需求高峰期之间的时间滞后。最后,我们提供了来自意大利和美国的经验证据,支持了我们模型分析的观点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f95/10275477/2c4291a7de86/pone.0286501.g001.jpg

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