Noda A, Takayama T, Ogawa Y, Sugimoto Y, Shibata T, Horiguchi Y, Kameya S, Nakanishi Y
Gastroenterol Jpn. 1986 Jun;21(3):255-61. doi: 10.1007/BF02774568.
Chemical studies were performed on all or part of four X-ray translucent (nonopaque) concretions and one protein plug to investigate a possible relationship between these substances, and to find the similarities and differences between these materials and pancreatic stone protein. Through elemental analysis, infrared absorption spectrometry, quantitative analysis of protein, and amino acid analysis, nonopaque concretions and protein plug were found to consist mainly of protein. One nonopaque concretion contained a very small amount of crystalline which differed greatly from calcite type calcium carbonate as observed in pancreatic calcified stones. The pattern of amino acid composition was very similar between the concentrations and the protein plug: rich in acidic amino acids, but poor in basic and aromatic residues. The aspartic acid content was the highest among detected amino acids. Comparison of amino acid composition between the nonopaque concretions which we analyzed and the pancreatic stone protein reported from Sarles' laboratory suggested that the concretions seem to contain some stone protein.
对4个X射线可透（不 opaque）的结石和1个蛋白栓的全部或部分进行了化学研究，以调查这些物质之间可能的关系，并找出这些材料与胰石蛋白之间的异同。通过元素分析、红外吸收光谱法、蛋白质定量分析和氨基酸分析，发现不 opaque结石和蛋白栓主要由蛋白质组成。1个不 opaque结石含有极少量的晶体，这与胰腺钙化结石中观察到的方解石型碳酸钙有很大不同。结石和蛋白栓之间的氨基酸组成模式非常相似：富含酸性氨基酸，但碱性和芳香族残基含量较低。在检测到的氨基酸中，天冬氨酸含量最高。我们分析的不 opaque结石与萨尔斯实验室报道的胰石蛋白之间的氨基酸组成比较表明，这些结石似乎含有一些结石蛋白。
